Encuesta nacional online aplicada en pacientes con enfermedad celíaca en Chile / A national online survey applied to patients with celiac disease in Chile
Rev. méd. Chile
; 139(7): 841-847, jul. 2011. ilus, tab
Article
em Es
| LILACS
| ID: lil-603135
Biblioteca responsável:
BR1.1
ABSTRACT
Background:
Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Its prevalence in Europe and the USA is 0.5 to 1 percent.Aim:
To analyze epidemiological aspects and degree of compliance with gluten-free diet (GFD) among Chilean individuals with CD. Material andMethods:
Subjects with confirmed or suspected CD were invited to answer an online survey published on the web at www.fundacionconvivir.cl. The answers were reinforced with a telephone interview.Results:
The survey was answered by 1212 subjects (79 percent females). Median age at diagnosis was 25.8 years (range 1 to 84 years), with a bimodal curve with two peaks at less than 3 years and at 20 to 40 years of age. The diagnosis was made only by serologic markers in 9 percent, only by intestinal biopsy in 17.5 percent, and by a combination of both methods in 70 percento. Conditions associated with CD were reported by 30 percent> of subjects and 20 percent> had relatives with CD. The GFD was strictly adhered to by 70 percent>, occasionally by 27 percent> and never by 3 percent>. Seventy five percent of subjects with a strict adherence to GFD had a favorable clinical response compared with 42 percent> of those with incomplete or lack of adherence (odds ratio 4.0, 95 percent> confidence intervals 2.8-5.7p < 0.01).Conclusions:
In 30 percent of respondents, the diagnosis of CD was not confirmed according to international guidelines that require serology and duodenal biopsy. One third of subjects recognized a poor compliance with GFD. Those with a strict adherence to it had a more favorable clinical course. However, 25 percent> did not experience a clinical improvement despite a strict GFD, a finding which requires further study.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Doença Celíaca
/
Cooperação do Paciente
/
Dieta Livre de Glúten
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
America do sul
/
Chile
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile