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A review of the epidemiology and treatment of Merkel cell carcinoma
Duprat, João Pedreira; Landman, Gilles; Salvajoli, João Victor; Brechtbühl, Eduard Rene.
Afiliação
  • Duprat, João Pedreira; Hospital do Câncer AC Camargo. Department of Skin Câncer. São Paulo. BR
  • Landman, Gilles; Hospital AC Camargo. São Paulo. BR
  • Salvajoli, João Victor; Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira. São Paulo. BR
  • Brechtbühl, Eduard Rene; Hospital do Câncer AC Camargo. Department of Skin Câncer. São Paulo. BR
Clinics ; Clinics;66(10): 1817-1823, 2011. tab
Article em En | LILACS | ID: lil-601919
Biblioteca responsável: BR1.1
ABSTRACT
Merkel cell carcinoma is a very rare and aggressive neoplasm. Due to its rarity, therapeutic guidelines are not well established, especially for regionally advanced disease. Articles in English, French, Italian, Portuguese, and Spanish from the last 20 years were identified in MEDLINE and reviewed. The key word "Merkel" was used for the search, relevant articles were selected, and their references were examined. The most important articles related to epidemiology, genesis and treatment were reviewed. The incidence of Merkel cell carcinoma is increasing due to the advancing age of the population, higher rates of sun exposure and an increasing number of immunocompromised individuals. With regard to etiology, the recently described Merkel Cell polyomavirus is thought to play a role. Either local or regional surgical intervention remains the standard of care, but adjuvant radiotherapy or radiotherapy as a primary treatment have been discussed as reasonable therapeutic options. An update on this rare neoplasia is essential because of its increasing incidence and changing treatment options.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Neoplasias Cutâneas / Carcinoma de Célula de Merkel Tipo de estudo: Guideline / Screening_studies Limite: Humans Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Neoplasias Cutâneas / Carcinoma de Célula de Merkel Tipo de estudo: Guideline / Screening_studies Limite: Humans Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil