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Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
Tilaoui, Mounir; Mouse, Hassan Ait; Jaafari, Abdeslam; Aboufatima, Rachida; Chait, Abderrahman; Zyad, Abdelmajid.
Afiliação
  • Tilaoui, Mounir; Sultan Moulay Slimane University. Faculty of Sciences and Technologies. Natural Substances, Cellular and Molecular Immuno-pharmacology Group. Laboratory of Biological Engineering. MA
  • Mouse, Hassan Ait; Sultan Moulay Slimane University. Faculty of Sciences and Technologies. Natural Substances, Cellular and Molecular Immuno-pharmacology Group. Laboratory of Biological Engineering. MA
  • Jaafari, Abdeslam; Sultan Moulay Slimane University. Faculty of Sciences and Technologies. Natural Substances, Cellular and Molecular Immuno-pharmacology Group. Laboratory of Biological Engineering. MA
  • Aboufatima, Rachida; Cadi Ayyad University. Faculty of Sciences Semlalia. Laboratory of Ecophysiology. MA
  • Chait, Abderrahman; Cadi Ayyad University. Faculty of Sciences Semlalia. Laboratory of Ecophysiology. MA
  • Zyad, Abdelmajid; Sultan Moulay Slimane University. Faculty of Sciences and Technologies. Natural Substances, Cellular and Molecular Immuno-pharmacology Group. Laboratory of Biological Engineering. MA
Rev. bras. farmacogn ; 21(4): 781-785, jul.-ago. 2011. ilus, graf, tab
Article em En | LILACS | ID: lil-596247
Biblioteca responsável: BR1.1
ABSTRACT
Artemisia herba-alba Asso., Asteraceae, is widely used in Morrocan folk medicine for the treatment of different health disorders. However, no scientific or medical studies were carried out to assess the cytotoxicity of A. herba-alba essential oil against cancer cell lines. In this study, eighteen volatile compounds were identified by GC-MS analysis of the essential oil obtained from the plant's aerial parts. The main volatile constituent in A. herba-alba was found to be a monoterpene, Verbenol, contributing to about 22 percent of the total volatile components. The essential oil showed significant antiproliferative activity against the acute lymphoblastic leukaemia (CEM) cell line, with 3 µg/mL as IC50 value. The anticancer bioactivity of Moroccan A. herba-alba essential oil is described here for the first time.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. bras. farmacogn Assunto da revista: FARMACIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Marrocos País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. bras. farmacogn Assunto da revista: FARMACIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Marrocos País de publicação: Brasil