Your browser doesn't support javascript.
loading
In vitro antifungal susceptibility of Candida spp. oral isolates from HIV-positive patients and control individuals
Brito, Graziella Nuernberg Back; Inocêncio, Aline Cássia; Querido, Sílvia Maria Rodrigues; Jorge, Antonio Olavo Cardoso; Koga-Ito, Cristiane Yumi.
Afiliação
  • Brito, Graziella Nuernberg Back; Univ Estadual Paulista. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. BR
  • Inocêncio, Aline Cássia; Univ Estadual Paulista. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. BR
  • Querido, Sílvia Maria Rodrigues; Univ Estadual Paulista. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. BR
  • Jorge, Antonio Olavo Cardoso; Univ Estadual Paulista. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. BR
  • Koga-Ito, Cristiane Yumi; Univ Estadual Paulista. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. BR
Braz. oral res ; 25(1): 28-33, Jan.-Feb. 2011. tab
Article em En | LILACS | ID: lil-595842
Biblioteca responsável: BR1.1
ABSTRACT
Oropharyngeal candidiasis is the most common fungal infection among HIV-positive patients. This condition can be treated with either systemic or topical antifungal agents; treatments are usually indicated empirically on the basis of clinical data. The knowledge of in vitro antifungal susceptibility is important to determine correct therapeutic guides for the treatment of fungal infections. Therefore, the objective of this study was to determine the antifungal susceptibility profile of oral Candida isolates from HIV-positive patients and control individuals. Amphotericin B, fluconazole, flucytosine, nystatin and ketoconazole were tested according to the methodology of microdilution proposed by the Clinical and Laboratory Standards Institute (CLSI); results were recorded in values of minimal inhibitory concentration (MIC). A total of 71 Candida isolates from HIV-positive patients were examined with the following species represented C. albicans (59), C. tropicalis (9), C. glabrata (1), C. guilliermondii (1) and C. krusei (1). A total of 15 Candida isolates were evaluated from control individuals comprised of 11 C. albicans and 4 C. tropicalis samples. Our results demonstrated that the tested antifungal agents showed good activity for most isolates from both groups; however, variability in MIC values among isolates was observed.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Candida / Infecções por HIV / Farmacorresistência Fúngica Múltipla / Antifúngicos Tipo de estudo: Guideline / Observational_studies Limite: Humans Idioma: En Revista: Braz. oral res Assunto da revista: ODONTOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Candida / Infecções por HIV / Farmacorresistência Fúngica Múltipla / Antifúngicos Tipo de estudo: Guideline / Observational_studies Limite: Humans Idioma: En Revista: Braz. oral res Assunto da revista: ODONTOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil