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Captaciones fisiológicas y variantes normales en el estudio PET/CT con (18)FDG / Normal variants and frequent pitfalls with (18)FDG PET/CT study
Rocío Estrada-Sánchez, Gisela del; Altamirano-Ley, Javier; Ochoa-Carrillo, Francisco Javier.
Afiliação
  • Rocío Estrada-Sánchez, Gisela del; C. T. Scanner del Sur. Unidad PET/CT. MX
  • Altamirano-Ley, Javier; Hospital Ángeles de las Lomas. Unidad PET/CT. MX
  • Ochoa-Carrillo, Francisco Javier; Instituto Nacional de Cancerología. Subdirección de Cirugía. MX
Cir. & cir ; Cir. & cir;75(6): 491-497, nov.-dic. 2007. ilus, tab
Article em Es | LILACS | ID: lil-568923
Biblioteca responsável: BR1.1
ABSTRACT

BACKGROUND:

Fluordeoxyglucose ((18)FDG) is the most common radiotracer used for PET/CT studies. It enters the cell because of the glucose transporter proteins (GLUTs) 1) erythrocytic membrane, skeletal muscle, lymphocytes, ovaries, breast; 2) pancreas, retina, erythrocytes; 3) adipocytes, ovaries, testis; 4) skeletal muscle, adipocytes, ovaries, myocardium; 5) breast, small intestine, testis, kidney, erythrocytes; 6) spleen, leucocytes, brain; 7) liver; 8) testis, brain; 9) liver, kidney; 10) liver, pancreas; 11) heart, muscle; 12) heart, prostate; 13) brain. We undertook this study to expand the knowledge about physiological uptake. Physiological uptake of (18)FDG was in brain, Waldeyer ring (adenoids, palatine tonsils, lingual tonsils), salivary glands (parotids, submandibular), tongue, vocal cords, cricoarythenoid muscle, thyroid, brown fat (supraclavicular, mediastinal, neck, pericardial fat, around kidney, around great vessels in the thorax, subdiaphragmatic, intercostals, paravertebral), myocardium, breast, thymus, contractive muscles, liver, spleen (similar to the liver), stomach, intestine, kidneys, bladder, uterus, ovaries, testes, bone marrow, esophagus, and atherosclerotic inflammatory plaque.

DISCUSSION:

False positives were as follows pneumoniae, tuberculosis, sarcoidosis, cryptococcosis, thrombosis, bronchitis, costochondritis, radiation pneumonitis, misregistration for respiratory movements, catheters, thyroid and adrenal adenomas, osteophytes, fractures, abscess, foreign body, surgical wounds, ostomies, prosthesis, degenerative joint diseases, osteomyelitis, amyloidosis, pancreatitis, myositis, gastritis, colitis, herpes zoster. (18)FDG should be injected 4-6 h after insulin administration because it will be concentrated in the muscles. The brown fat raises its uptake 50% in late images.

CONCLUSIONS:

It is vital to know the most frequent sites of physiological uptake in the (18)FDG PET/CT studies to identify those regions that occasionally present hypermetabolism but that are not related to neoplastic tumors. This must be taken into consideration in the evaluation of PET/CT studies.
Assuntos
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Tomografia Computadorizada por Raios X / Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons Limite: Humans Idioma: Es Revista: Cir. & cir Assunto da revista: CIRURGIA GERAL Ano de publicação: 2007 Tipo de documento: Article País de afiliação: México País de publicação: México
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Tomografia Computadorizada por Raios X / Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons Limite: Humans Idioma: Es Revista: Cir. & cir Assunto da revista: CIRURGIA GERAL Ano de publicação: 2007 Tipo de documento: Article País de afiliação: México País de publicação: México