Antiproliferative effect of indomethacin in Aedes albopictus (mosquito) cells
Rev. Ciênc. Méd. Biol. (Impr.)
; 8(1): 14-17, jan.-abr. 2009. graf
Article
em En
| LILACS, BBO
| ID: lil-545801
Biblioteca responsável:
BR337.1
ABSTRACT
Non-steroidal and anti-inflammatory drugs (NSAIDs) are a class of pharmacological agents that are tradicionally used for their anti-cyclooxigenase properties in the treatment of inflammation and other associated diseases. Recently, however, it has been demonstrated that several NSAIDs exhibit antiproliferative effects in various animal models and in vitro experiments. In this paper we demonstrated that treatment of Aedes albopictus cells (mosquito) with indomethacin results in a reduction of normal growth rate. Cells treated with 100 mM indomethacin exhibited a profound time dependent reduction in their proliferation rate over the 96 h test period.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
BBO
/
LILACS
Assunto principal:
Anti-Inflamatórios não Esteroides
/
Indometacina
/
Aedes
Idioma:
En
Revista:
Rev. Ciênc. Méd. Biol. (Impr.)
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil