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Transurethral resection of the prostate for the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia: how much should be resected?
Antunes, Alberto A; Srougi, Miguel; Coelho, Rafael F; Leite, Katia R; Freire, Geraldo de C.
Afiliação
  • Antunes, Alberto A; University of Sao Paulo. Medical School. Division of Urology. Sao Paulo. BR
  • Srougi, Miguel; s.af
  • Coelho, Rafael F; University of Sao Paulo. Medical School. Division of Urology. Sao Paulo. BR
  • Leite, Katia R; University of Sao Paulo. Medical School. Division of Urology. Sao Paulo. BR
  • Freire, Geraldo de C; University of Sao Paulo. Medical School. Division of Urology. Sao Paulo. BR
Int. braz. j. urol ; 35(6): 683-691, Nov.-Dec. 2009. tab, ilus
Article em En | LILACS | ID: lil-536801
Biblioteca responsável: BR1.1
ABSTRACT

Objective:

To assess the impact of the percent of resected tissue on the improvement of urinary symptoms. Materials and

methods:

The study included a prospective analysis of 88 men with benign prostatic hyperplasia. Patients were divided in three groups according to the percent of resected tissue Group 1 < 30 percent; Group 2, 30 percent to 50 percent; and Group 3, > 50 percent. Each patient was re-evaluated 3 months after surgery. We assessed the international prostatic symptom score, nocturia and serum prostate specific antigen levels.

Results:

All patients presented a significant decrease on mean International Prostate System Score (IPSS) (23 to 5.9), Quality of Life (QoL) (4.9 to 1.0) and nocturia (3.2 to 1.9). Variation in the IPSS was 16.7, 16.6 and 18.4 for patients from Group 1, 2 and 3 respectively (P = 0.504). Although the three groups presented a significant decrease in QoL, patients in Group 3 presented a significantly greater decrease when compared to Group 1. Variation in QoL was 3.1, 3.9 and 4.2 for patients from Group 1, 2 and 3 respectively (p = 0.046). There was no significant difference in nocturia variation according to the percent of resected tissue (p = 0.504). Median pre and postoperative PSA value was 3.7 and 1.9 ng/mL respectively. Patients from Group 1 did not show a significant variation (p = 0.694). Blood transfusions were not required in any group.

Conclusions:

Resection of less than 30 percent of prostatic tissue seems to be sufficient to alleviate lower urinary tract symptoms related to benign prostate hyperplasia. However, these patients may not show a significant decrease in serum PSA level.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Hiperplasia Prostática / Transtornos Urinários / Ressecção Transuretral da Próstata Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Aged / Humans / Male Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2009 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Hiperplasia Prostática / Transtornos Urinários / Ressecção Transuretral da Próstata Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Aged / Humans / Male Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2009 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil