Bipolar disorder complicated by selfmutilation: neurofunctional changes demonstrated by Tc99mHMPAO Neuro SPECT
Rev. med. nucl. Alasbimn j
; 10(38)Oct. 2007. ilus, tab
Article
em En
| LILACS
| ID: lil-480476
Biblioteca responsável:
CL1.1
ABSTRACT
We report neurofunctional changes in patients with selfmutilation and bipolar disorder. We compared a sample of 29 patients with selfmutilation and bipolar disorder with a group of 20 patients with bipolar disorder without selfmutilation. Furthermore we had an additional control of 22 patients with Major Depression without selfmutilation. Among the findings in selfmutilation, increased anterior dorsal-ventral thalamic perfusion stands out, this is associated with decreased perfusion in the perilimbic area (areas 24, 32 and 23 of Brodmann). There are multiple reports relating in animals and humans selfmutilation with hypoalgesia, anesthesia and disestesias; an hypothesis can be formulated relating self mutilation phenomena with a dysfunction of thalamus and perilimbic circuits associated with nosoceptive circuits and somato-psychic conscience.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Automutilação
/
Transtorno Bipolar
/
Tomografia Computadorizada de Emissão de Fóton Único
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Rev. med. nucl. Alasbimn j
Assunto da revista:
MEDICINA NUCLEAR
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile