Your browser doesn't support javascript.
loading
Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana / Prevalence of metronidazole, clarithromycin and tetracycline resistance in Helicobacter pylori isolated from Chilean patients
Vallejos M., Cristian; Garrido O., Leonardo; Cáceres L., Dante; Madrid, Ana María; Defilippi, Claudia; Defilippi C., Carlos; Toledo A., Héctor.
Afiliação
  • Vallejos M., Cristian; Universidad de Chile. Facultad de Medicina. ICBM. Programa de Biología Celular y Molecular. Santiago. CL
  • Garrido O., Leonardo; Universidad de Chile. Facultad de Medicina. ICBM. Programa de Biología Celular y Molecular. Santiago. CL
  • Cáceres L., Dante; Universidad de Chile. Facultad de Medicina. Escuela de Salud Pública. División de Epidemiología. Santiago. CL
  • Madrid, Ana María; Universidad de Chile. Hospital Clínico. Unidad de Gastroenterología. Departamento de Medicina. Santiago. CL
  • Defilippi, Claudia; Universidad de Chile. Hospital Clínico. Unidad de Gastroenterología. Departamento de Medicina. Santiago. CL
  • Defilippi C., Carlos; Universidad de Chile. Hospital Clínico. Unidad de Gastroenterología. Departamento de Medicina. Santiago. CL
  • Toledo A., Héctor; Universidad de Chile. Facultad de Medicina. ICBM. Programa de Biología Celular y Molecular. Santiago. CL
Rev. méd. Chile ; 135(3): 287-293, mar. 2007. tab
Article em Es | LILACS | ID: lil-456613
Biblioteca responsável: BR1.1
ABSTRACT

Background:

Helicobacter pylori is a pathogenic bacterium that infects a significant number of individuals. At present, therapeutic strategies to eradicate this bacterium depend on our knowledge of its resistance to antimicrobials.

Aims:

To evaluate the primary resistance of H pylori to metronidazole (Mtz), clarithromycin (Cla), and tetracycline (Tet) in symptomatic out-patients. Material and

Methods:

Fifty independent isolates of H pylori were obtained by endoscopy-assisted gastric biopsy from patients attending the University of Chile Clinical Hospital, that previously had not been treated with an eradication regime against this bacterium. The minimal inhibitory concentration of each antimicrobial was determined by agar dilution method.

Results:

Forty five and 27 percent of the isolates were found to be resistant to Mtz and Tet, respectively; the majority of these resistant isolates were from patients older than 21 years. Twenty percent of isolates were resistant to Cla; these were distributed evenly among different ages. Thirty two percent of the isolates were resistant to two or more of the antimicrobials.

Conclusions:

The high frequency of naturally occurring, antimicrobial-resistant strains of H pylori poses a national and world-wide problem for public health.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Tetraciclina / Helicobacter pylori / Claritromicina / Farmacorresistência Bacteriana Múltipla / Metronidazol / Antibacterianos Tipo de estudo: Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male País/Região como assunto: America do sul / Chile Idioma: Es Revista: Rev. méd. Chile Assunto da revista: MEDICINA Ano de publicação: 2007 Tipo de documento: Article / Project document País de afiliação: Chile País de publicação: Chile
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Tetraciclina / Helicobacter pylori / Claritromicina / Farmacorresistência Bacteriana Múltipla / Metronidazol / Antibacterianos Tipo de estudo: Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male País/Região como assunto: America do sul / Chile Idioma: Es Revista: Rev. méd. Chile Assunto da revista: MEDICINA Ano de publicação: 2007 Tipo de documento: Article / Project document País de afiliação: Chile País de publicação: Chile