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Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case / Idiopathic Lambert-Eaton myasthenic syndrome
Guevara O., Carlos; Pedraza C., Luis; Idiáquez C., Juan; Delgado M., Marcela.
Afiliação
  • Guevara O., Carlos; Centro de Referencia de Salud Dr. Salvador Allende Gossens. Unidad de Neurología. Pudahuel. CL
  • Pedraza C., Luis; Universidad de Chile. Hospital Clínico José Joaquín Aguirre. Servicio de Neurología-Neurocirugía. Santiago. CL
  • Idiáquez C., Juan; Universidad Católica de Chile. Hospital Clínico. Laboratorio de Evaluación Autonómica. Santiago. CL
  • Delgado M., Marcela; Centro de Referencia de Salud Dr. Salvador Allende Gossens. Pudahuel. CL
Rev. méd. Chile ; 134(2): 217-223, feb. 2006. tab, graf
Article em Es | LILACS | ID: lil-425972
Biblioteca responsável: BR1.1
ABSTRACT
Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels. The clinical features of patients with LEMS are muscle weakness and autonomic dysfunction. We report a 40 years old man with a four years history of proximal weakness, absent tendon reflexes and dry mouth. The diagnosis was confirmed by characteristic electromyographic findings, showing a low-amplitude muscle response that increased dramatically after activation. Circulating antibodies to voltage-gated calcium channel were present. The search for malignant tumors was negative. The patient was treated with prednisone and azathioprine and after four months, he was able to walk and signs of autonomic dysfunction started to subside.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Síndrome Miastênica de Lambert-Eaton Limite: Adult / Humans / Male Idioma: Es Revista: Rev. méd. Chile Assunto da revista: MEDICINA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Síndrome Miastênica de Lambert-Eaton Limite: Adult / Humans / Male Idioma: Es Revista: Rev. méd. Chile Assunto da revista: MEDICINA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile