Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001

Dal Fabbro, Márcia Maria Ferrairo Janini; Cunha, Rivaldo Venâncio da; Paniago, Anamaria Mello Miranda; Lindenberg, Andréa de Siqueira C; Freitas, Gisele Maria Brandão de; Nogueira, Susie Andries

Dal Fabbro, Márcia Maria Ferrairo Janini; Cunha, Rivaldo Venâncio da; Paniago, Anamaria Mello Miranda; Lindenberg, Andréa de Siqueira C; Freitas, Gisele Maria Brandão de; Nogueira, Susie Andries.

Afiliação

Dal Fabbro, Márcia Maria Ferrairo Janini; Infecto-Parasitic Center. BR
Cunha, Rivaldo Venâncio da; Federal University of Mato Grosso do Sul. University Hospital. Infectious and Parasitic Diseases Department. Campo Grande. BR
Paniago, Anamaria Mello Miranda; Federal University of Mato Grosso do Sul. University Hospital. Infectious and Parasitic Diseases Department. Campo Grande. BR
Lindenberg, Andréa de Siqueira C; Infecto-Parasitic Center. BR
Freitas, Gisele Maria Brandão de; Infecto-Parasitic Center. BR
Nogueira, Susie Andries; Clementino Fraga Filho Hospital. Infectious and Parasitic Diseases Department. Rio de Janeiro. BR

Braz. j. infect. dis ; Braz. j. infect. dis;9(1)Feb. 2005. tab, graf

Article em En | LILACS | ID: lil-404304

Biblioteca responsável: BR1.1

RESUMO

RESUMO

This prospective study, involving 76 pregnant women infected with HIV, paired with their 79 exposed infants, was carried out between May 1996 and October 2001, at the Reference Department for Pregnant Women Infected with HIV in Campo Grande, Mato Grosso do Sul. The mean age of the pregnant women was 24 years; 88 percent (67/76) apparently were infected due to sexual practices; 88 percent (67/76) were housewives; 823 percent (63/76) graduated from junior high school; 14.5 percent (11/76) reported co-infection with Hepatitis C, 9.2 percent with Syphilis; 51 percent (39/76) learned the diagnosis during prenatal care; 67 percent (51/76) reported HIV clinical symptomatology and 9.2 percent (7/76) reported opportunistic infections. Elective cesareans were performed in 57 percent (43/76). The mean gestational age at delivery was 38 weeks and we found 12.5 percent (10/80) pronatis; 97 percent (74/76) had a ruptured membrane time after less than four hours and one child (1.3 percent) was nursed. ACTG 076 Protocol (AIDS Clinical Trial Group 076) was used in 80 percent (61/76) of the pregnant women, with 100 percent adherence; 62 percent (38/61) used zidovudine plus another antiretroviral in the gestation; 92 percent (73/79) of the infants used zidovudine after the birth and 19 percent (14/73) used zidovudine and lamivudine. The transmission rate in this study was 2.5 percent.

Assuntos

Adolescente; Adulto; Feminino; Humanos; Recém-Nascido; Gravidez; Fármacos Anti-HIV/uso terapêutico; Infecções por HIV/transmissão; Transmissão Vertical de Doenças Infecciosas; Complicações Infecciosas na Gravidez; Brasil/epidemiologia; Estudos de Coortes; Ensaio de Imunoadsorção Enzimática; Seguimentos; Infecções por HIV/diagnóstico; Infecções por HIV/prevenção & controle; Lamivudina/uso terapêutico; Estudos Prospectivos; Fatores de Risco; Carga Viral; Zidovudina/uso terapêutico

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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Complicações Infecciosas na Gravidez / Infecções por HIV / Transmissão Vertical de Doenças Infecciosas / Fármacos Anti-HIV Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Newborn / Pregnancy País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

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