Cyclophosphamide identification in wipe test by GC-MS and solid phase extraction
RBCF, Rev. bras. ciênc. farm. (Impr.)
; RBCF, Rev. bras. ciênc. farm. (Impr.);40(1): 67-73, jan.-mar. 2004. tab, graf
Article
em En
| LILACS
| ID: lil-391014
Biblioteca responsável:
BR40.1
RESUMO
In this study cyclophosphamide was quantified after adapting a prior analytical method using gas chromatography-mass spectrometry after solid phase purification and derivatization with trifluoroacetic anhydride. The analyte was measured by analysis in wipe test from infusion bags, which may be contaminated by contact with the gloves used during preparation of the drugs. Surface of bag contaminated may be an important source of contamination for workers in the others chemoterapy handling areas, such as administration rooms. This drug, in fact, is one of the most frequently used alkylating antineoplastic agents for different types of tumors and it is furthermore classified as a human carcinogen by IARC...
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Preparações Farmacêuticas
/
Exposição Ocupacional
/
Ciclofosfamida
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
RBCF, Rev. bras. ciênc. farm. (Impr.)
Assunto da revista:
BIOQUIMICA
/
FARMACIA
/
FARMACOLOGIA
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil