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Interleukin-2 receptor serum concentrations in normal pregnancy and pre-eclampsia
Romero-Adrián, Tania; Ruiz, Ana; Molina-Vílchez, Rafael; Estévez, Jesus; Atencio, Ricardo.
Afiliação
  • Romero-Adrián, Tania; Universidad del Zulia. Facultad de Medicina. Maracaibo. VE
  • Ruiz, Ana; Universidad del Zulia. Facultad de Medicina. Maracaibo. VE
  • Molina-Vílchez, Rafael; Instituto Venezolano de los Seguros Sociales. Hospital Manuel Noriega Trigo. VE
  • Estévez, Jesus; Universidad del Zulia. Facultad de Medicina. Maracaibo. VE
  • Atencio, Ricardo; Universidad del Zulia. Facultad de Medicina. Maracaibo. VE
Invest. clín ; Invest. clín;43(2): 73-78, jun. 2002.
Article em En | LILACS | ID: lil-330978
Biblioteca responsável: BR1.1
ABSTRACT
The purpose of this research was to assess interleukin-2 receptor serum levels in normal pregnancy and pre-eclampsia. Sera from 90 healthy pregnant women (30 for each trimester), 30 with pre-eclampsia and a group of 30 healthy non-pregnant were analyzed. Soluble interleukin-2 receptor was measured by specific double antibody enzymatic immunoassay (ELISA). Results were 267.5 +/- 12.3 (mean +/- s.e.m) pg/mL in the uncomplicated first trimester sample, 300.9 +/- 14.5 pg/mL in the second trimester and 248.8 +/- 12.5 pg/mL in the third. The non-pregnant control group had 443.7 +/- 39.6 pg/mL, significantly different from normal pregnancy in all trimesters (p < 0.001). The concentration in pre-eclamptic patients was 382.2 +/- 24.2 pg/mL, with p < 0.01 with regard to the normal third trimester group. The conclusion is that interleukin-2 receptor serum levels diminish in normal pregnancy and rise in preeclampsia. The first finding seems to be a protective mechanism to the fetal allograft. The latter, point to increased cellular activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Pré-Eclâmpsia / Gravidez / Receptores de Interleucina-1 Limite: Adolescent / Adult / Female / Humans Idioma: En Revista: Invest. clín Assunto da revista: Biologia / MEDICINA / Relatos de Casos Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Venezuela País de publicação: Venezuela
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Pré-Eclâmpsia / Gravidez / Receptores de Interleucina-1 Limite: Adolescent / Adult / Female / Humans Idioma: En Revista: Invest. clín Assunto da revista: Biologia / MEDICINA / Relatos de Casos Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Venezuela País de publicação: Venezuela