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Hippuric acid in urine: reference values
Siqueira, Maria Elisa P. B; Paiva, Maria José N.
Afiliação
  • Siqueira, Maria Elisa P. B; Escola de Farmácia e Odontologia de Alfenas. Departamento de Análises Clínicas e Toxicológicas. BR
  • Paiva, Maria José N; Escola de Farmácia e Odontologia de Alfenas. Departamento de Análises Clínicas e Toxicológicas. BR
Rev. saúde pública ; Rev. saúde pública;36(6): 723-727, dez. 2002. tab, graf
Article em En | LILACS | ID: lil-326387
Biblioteca responsável: BR67.1
RESUMO

OBJECTIVE:

To establish reference values for hippuric acid (HA) excreted in the urine, and to evaluate the impact of age, gender, alcohol, and tobacco, on these levels in a population nonexposed to toluene.

METHODS:

Reference values for hippuric acid in urine were determined in 115 toluene nonexposed healthy volunteers, from Alfenas city, Southeastern Brazil. A questionnaire was applied to each volunteer and data on occupational and personal habits were collected. Biochemical and hematological analyses were used to confirm the volunteers' good health condition. Reference values were expressed in g HA/g urine creatinine, as mean Ý standard deviation (x Ý SD), median, 95 percent confidence interval (95 percentCI), 95th percentile, and upper reference value (URV, mean +2 SD).

RESULTS:

Reference values of hippuric acid in urine were mean Ý standard deviation =0.18Ý0.10; median =0.15; 95 percent confidence interval =0.16Ý0.20; 95th percentile = 0.36 and upper reference value (URV, mean +2 SD) =0.38. Statistically significant differences in urinary HA (Wilcoxon - Mann/Whitney, p<0.05) were observed for different genders and age groups. Alcohol ingestion and smoking habit did not significantly affect the results.

CONCLUSIONS:

The reference values of hippuric acid in urine can be used in biomonitoring programs of workers occupationally exposed to toluene, especially in the southern region of the state of Minas Gerais. Age and gender may affect the HA reference values
Assuntos
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Ácido p-Aminoipúrico / Valores de Referência / Tolueno / Urina Idioma: En Revista: Rev. saúde pública Assunto da revista: SAUDE PUBLICA Ano de publicação: 2002 Tipo de documento: Article / Congress and conference País de afiliação: Brasil País de publicação: Brasil
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Ácido p-Aminoipúrico / Valores de Referência / Tolueno / Urina Idioma: En Revista: Rev. saúde pública Assunto da revista: SAUDE PUBLICA Ano de publicação: 2002 Tipo de documento: Article / Congress and conference País de afiliação: Brasil País de publicação: Brasil