Experimental infection of canine peritoneal macrophages with visceral and dermotropic Leishmania strains
Mem. Inst. Oswaldo Cruz
; 94(5): 645-8, Sept. 1999. ilus
Article
em En
| LILACS
| ID: lil-241325
Biblioteca responsável:
BR1.1
RESUMO
A study was carried out using macrophages cultured from the peritoneal exudate of dogs infected in vitro with three species of Leishmania L. (L.) chagasi, L. (Viannia) braziliensis and L. (L.) amazonensis with the aim of investigating the growth kinetics and infectivity of these species in the host cell. Results were expressed as the percentage of macrophages infected measured at 24 hr intervals over six days in RPMI - 1640 culture medium at a temperature of 34-35oC. The findings open the possibility of using canine peritoneal cells as a model for the screenning of leishmanicide drugs and to study the pathogenesis of these species.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Técnicas In Vitro
/
Macrófagos Peritoneais
/
Leishmania
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
MEDICINA TROPICAL
/
PARASITOLOGIA
Ano de publicação:
1999
Tipo de documento:
Article
País de publicação:
Brasil