Caracteristicas histopatologicas hepaticas en pacientes com sueros anti HCV reactivos / Liver histopatlological characteristics in patients with anti-HCV-positive sera
Acta gastroenterol. latinoam
; Acta gastroenterol. latinoam;27(1): 15-8, mar. 1997. tab
Article
em Es
| LILACS
| ID: lil-196658
Biblioteca responsável:
BR1.1
ABSTRACT
In order to have knowledge on the histopatologic characteristics of the HCV infections in our geographical area and its relation with some epidemiologic variables, a serie of 54 biopsias of Anti HCV (R) patients was analized. The histologic lesions found in this study correspond mostly to patients with relatively early infections, on the contrary to other studies of the some kind. The most frequent histopathologic diagnosis were crhonic hepatitis 38/54 (70.4 percent), steatosis 4/54 (7.4 percent) and 12/54 (22.2 percent) with no changes. The presence of lymphoid follicles in the portal tracts was the most frequent histological change in this series (66.7 percent), followed by the alteration in bile ducts (53.7 percent); they occurred in a significally higher proportion in the biopsies which had a diagnosis of chronic hepatitis (p=0.02) (p=0.000002). The presence of steatosis and acidophilic bodies in the acinus were found in nearly one third of the biopsies. This findings suggest that the hepatic damage in the anti HCV reactive patients might take through inmunologic mechanisms and citopatic direct action. It was not found that histologic changes produced by HCV might differ according to epidemiologic variables (post-tranfutional, drug abuse IV and sporadic).
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Hepatite C
/
Fígado
Limite:
Adult
/
Female
/
Humans
País/Região como assunto:
America do sul
/
Argentina
Idioma:
Es
Revista:
Acta gastroenterol. latinoam
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
1997
Tipo de documento:
Article
País de publicação:
Argentina