Multifactorial control of water and saline intake: role of alpha2-adrenoceptors
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;30(4): 497-502, Apr. 1997. ilus, tab, graf
Article
em En
| LILACS
| ID: lil-191388
Biblioteca responsável:
BR1.1
RESUMO
Water and saline intake is controlled by several mechanisms activated during dehydration. Some mechanisms, such as the production of angiotensin II and unloading of cardiovascular receptors, activate both behaviors, while others, such as the increase in blood osmolality or sodium concentration, activate water, but inhibit saline intake. Aldosterone probably activates only saline intake. Clonidine, an alpha2-adrenergic agonist, inhibits water and saline intake induced by these mechanisms. One model to describe the interactions between these multiple mechanisms is a wire-block diagram, where the brain circuit that controls each intake is represented by a summing point of its respective inhibiting and activating factors. The alpha2-adrenoceptors constitute an inhibitory factor common to both summing points.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Sistema Renina-Angiotensina
/
Cloreto de Sódio
/
Norepinefrina
/
Clonidina
/
Receptores Adrenérgicos alfa 2
/
Agonistas alfa-Adrenérgicos
/
Desidratação
/
Ingestão de Líquidos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
/
Rev. bras. pesqui. méd. biol
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1997
Tipo de documento:
Article
/
Congress and conference
País de publicação:
Brasil