Terapia génica: ficcion o realidad / Gene therapy: fact or fantasy
Rev. méd. Chile
; 124(2): 237-47, feb. 1996.
Article
em Es
| LILACS
| ID: lil-173327
Biblioteca responsável:
CL1.1
ABSTRACT
The great advances in molecular biology have encouraged the treatment of diseases through gene intervention. According to present knowledge, all diseases somehow have their origin or are related to genes. Different stages must be overcome to intervene in genes a) Identification of the genes to intervene. Methodologies have been developed and a number of genes identified b) Codification of its structure. The technology for this purpose is already know and the process had been automated c) Locate the adequate vector that, without damaging the cell, is capable to introduce in nucleus the genetic material. There are many studied alternatives. However the ideal vector, that would select the target cells, be risk-free and guarantee prolonged results, has not been found yet d) To achiev the gene expression, codifying the respective protein or its inhibition, according to the case. Some success has been obtained in this field, but technology has to be improved to obtain a uniform and satisfactory response. Advances achieved in the last years have been impressive and technologies will presumably continue to improve
Buscar no Google
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Engenharia Genética
Limite:
Humans
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
1996
Tipo de documento:
Article
País de publicação:
Chile