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Acute effects on bone marrow after association between Radiosensitizer and X rays-NN/N method
Interciencia ; Interciencia;19(2): 75-8, mar.-abr. 1994. ilus
Article em En | LILACS | ID: lil-163405
Biblioteca responsável: VE1.1
RESUMO
A histopathological and morphometric study was performed in the bone marrow of mice after association of cisdiamminedi-choroplatinum II (3.0 mg/kg) plus X-rays (103.20 mC/Kg 400R). Rstimation of bone marrow effects was assessed by counting the number of non nucleated-erythrocytes (NN) and nucleated (N) cells, and establishing (NN/N) ratio. The morphomeric method used correlates and makes possible quantification of histopathologic changes of bone marrow through relation of vascular stroma and cellular parenchyma. It can be used as a biological dosimetry parameter and to estimate injury and recovery of hematologic evolution of different myelotoxic agents
Assuntos
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Coleções: 01-internacional Base de dados: LILACS Assunto principal: Radiometria / Íons Tipo de estudo: Risk_factors_studies Idioma: En Revista: Interciencia Assunto da revista: MEDICINA Ano de publicação: 1994 Tipo de documento: Article País de publicação: Venezuela
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Coleções: 01-internacional Base de dados: LILACS Assunto principal: Radiometria / Íons Tipo de estudo: Risk_factors_studies Idioma: En Revista: Interciencia Assunto da revista: MEDICINA Ano de publicação: 1994 Tipo de documento: Article País de publicação: Venezuela