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Antagonismo do flumazenil ao flunitrazepam / Flunitrazepam with flumazenil
Rev. bras. anestesiol ; Rev. bras. anestesiol;43(5): 297-302, set.-out. 1993. ilus, tab
Article em Pt | LILACS | ID: lil-159139
Biblioteca responsável: BR14.1
ABSTRACT
Flumazenil is a competitive inhibitor of the specific biding of benzodiazepines to central nervous system receptor sites and it is valuable in reversing their sedative effect. Twenty-four healthy patients (ASA I and II), both male and female, with age between 19 and 58 years and weight between 46 and 79 kg, scheduled for elective surgery under flunitrazepam oral premedication and intravenous sedation after spinal anesthesia, were submitted to a trial with flumazenil for reversal of sedation. Judged by the degree of sedaation, comprehension, cooperation and time and space orientation, flumazenil showed good results. Only 12 por cent of the patients presented resedation after 120 minutes. No adverse effect was observed.
Assuntos
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Coleções: 01-internacional Base de dados: LILACS Assunto principal: Período de Recuperação da Anestesia / Flumazenil / Flunitrazepam / Anestesia Epidural Limite: Adult / Humans Idioma: Pt Revista: Rev. bras. anestesiol Assunto da revista: ANESTESIOLOGIA Ano de publicação: 1993 Tipo de documento: Article País de publicação: Brasil
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Coleções: 01-internacional Base de dados: LILACS Assunto principal: Período de Recuperação da Anestesia / Flumazenil / Flunitrazepam / Anestesia Epidural Limite: Adult / Humans Idioma: Pt Revista: Rev. bras. anestesiol Assunto da revista: ANESTESIOLOGIA Ano de publicação: 1993 Tipo de documento: Article País de publicação: Brasil