Eficacia e seguranca do extrato seco da semente de castanha-da India no traamento da insuficiencia venosa cronica de membros inferiores / Efficacy and safety on use of dried horse chestnut extract in the treatmente of chronic venous insufficiency of the limbs.
RBM rev. bras. med
; RBM rev. bras. med;50(11): 1563-5, nov. 1993. tab
Article
em Pt
| LILACS
| ID: lil-131438
Biblioteca responsável:
BR394.1
ABSTRACT
This is a double-blind, randomized, placebo-controled, parallel study of the use of dried horse chestnut extract (Venostasin Retard) inchronic venous insufficiency of the limbs. Fifty-one patients were enrolled, divided in two groups, active (N=25) and placebo (N=26), and received treatment fortwenty days. The following parameters were evaluated telangiectasy, perimaleolar oedema, disestesy vascular congestion, blood ebling, ocre dermatitis, ulceration, burning, lead-footfeeling, effort incapacity, and others like pains or itching. Almost all these parameters showed a statistically significant improvement or a strong trend of improvement in the active group, except telangiectasy, perimaleolar oedema and ulceration. Adverse effects were unfrecquent and mild. In conclusion, the dried horse chestnut extract (Venostasin Retard) was efficaciuos regarding to the treatment of chronic venous insuciency of the limbs, and presented hight levels of safety and tolerance
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Flebite
/
Insuficiência Venosa
Tipo de estudo:
Clinical_trials
Idioma:
Pt
Revista:
RBM rev. bras. med
Assunto da revista:
MEDICINA
Ano de publicação:
1993
Tipo de documento:
Article
País de publicação:
Brasil