Carbonylative negishi-type coupling of 2-Iodoglycals with alkyl and aryl halides
European J Org Chem, v. 2019, n. 44, p. 7384-7388, nov. 2019
Article
em En
| SES-SP, SESSP-IBPROD, SES-SP
| ID: bud-2886
Biblioteca responsável:
BR78.1
ABSTRACT
C-Glycosides are valuable organic compounds in the field of medicinal chemistry due to their ubiquity inside living systems and pronounced biological activity. Herein, we describe an approach to alkyl-ketones bearing glycal units via the Pd-catalyzed carbonylative coupling of 2-iodoglycals and alkyl and aryl halides. Examples bearing a variety of functional groups are presented as well as a mechanistic proposal for this transformation.
Texto completo:
1
Coleções:
06-national
/
BR
Base de dados:
SES-SP
/
SESSP-IBPROD
Idioma:
En
Revista:
European J Org Chem
Ano de publicação:
2019
Tipo de documento:
Article