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Identificación de DNA de papilomavirus humano en condilomas anogenitales de una población masculina / DNA identification of human papillomavirus in anogenital condyloma of a male population
Turazza, Estela Ines; Ojeda, R. D; Ratto, P; Barrera, A; Ríos, Amanda; Kahn, T; Bercovich, J; Jaimovich, L; Grinstein, S.
Afiliação
  • Turazza, Estela Ines; Hospital de Ninos R. Gutierrez. Laboratorio de Virología. Buenos Aires. Argentina
  • Ojeda, R. D; Hospital de Ninos R. Gutierrez. Laboratorio de Virología. Buenos Aires. Argentina
  • Ratto, P; Hospital de Ninos R. Gutierrez. Laboratorio de Virología. Buenos Aires. Argentina
  • Barrera, A; Hospital Muniz. Departamento de Dermatologia. Argentina
  • Ríos, Amanda; Hospital Durand. Departamento de Dermatologia. Buenos Aires. Argentina
  • Kahn, T; German Cancer Research Center. Heidelberg. Alemania
  • Bercovich, J; Hospital de Ninos R. Gutierrez. Laboratorio de Virología. Buenos Aires. Argentina
  • Jaimovich, L; Hospital Durand. Departamento de Dermatologia. Buenos Aires. Argentina
  • Grinstein, S; Hospital de Ninos R. Gutierrez. Laboratorio de Virología. Buenos Aires. Argentina
Medicina (B.Aires) ; 53(3): 197-201, may.-jun. 1993.
Article em Es | BINACIS | ID: bin-7450
Biblioteca responsável: BR1.1
ABSTRACT
Human Papillomaviruses (HPV) are the cause of benign human anogenital lesions where HPV 6 and HPV 11 are most commonly found. Conversely, HPV 16, 18, 31 and 33 are frequently detected in genital carcinomas and are thus considered as oncogenic types. In order to analyze the prevalence of specific HPV types in an Argentine male population, 43 anogenital lesions from different patients with diagnosis of condyloma acuminata were analyzed. These lesions were localized in different regions of the male genitalia comprising the corona glandis, urethral meatus, skin of the penis, scrotum and anus. The biopsies were screened for the presence of HPV 6, 11, 16, 18, 30, 31 and 33 by Southern blot at different stringent conditions of hybridization (Tm -48 degrees C and Tm -20 degrees C). HPV DNA was found in 41 examined cases (95.3) with a clear prevalence of HPV 6 and HPV 11 types (51.2 and 23.3 respectively). Six samples (14.0) were positive only under nonstringent conditions of hybridization. Mixed infections between HPV 16, 18, 30, 31, 33 or a HPV 30 related type with HPV 6 or HPV 11 were detected in 8 specimens (18.6). Only one case was between HPV 16 and HPV 30. Two additional samples were only positive for HPV 30. Experiments in progress about the prevalence of HPV types in female lesions as well as in normal subjects will contribute to complete the description of the epidemiology of these infections in Argentina.(Au)
Assuntos
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Coleções: 06-national / AR Base de dados: BINACIS Assunto principal: Infecções Tumorais por Vírus / DNA Viral / Condiloma Acuminado / Doenças dos Genitais Masculinos / Papillomavirus Humano Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Adult / Aged / Humans / Male Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 1993 Tipo de documento: Article
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Coleções: 06-national / AR Base de dados: BINACIS Assunto principal: Infecções Tumorais por Vírus / DNA Viral / Condiloma Acuminado / Doenças dos Genitais Masculinos / Papillomavirus Humano Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Adult / Aged / Humans / Male Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 1993 Tipo de documento: Article