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Insulinoterapia intensificada en el manejo de la diabetes pregestacional. / [Intensified insulin therapy in the management of gestational diabetes]
Litwak, L E; Mileo Vaglio, R; Fried, T; De Sancho, H; Alvarez, A; Althabe, O; Gutman, R A.
Afiliação
  • Gutman, R A; Servicio de Endocrinología, Hospital Italiano, Buenos Aires, Argentina..
Medicina (B.Aires) ; 52(6): 523-33, 1992.
Article em Es | BINACIS | ID: bin-51040
Biblioteca responsável: AR2.1
ABSTRACT
A total of 35 pregnancies in 28 Pregestational Diabetic Patients (PDP) were followed with the goal of achieving and maintaining near normoglycemia (as many pre-postprandial glycemias as possible between 60-140 mg/dl); 13 patients (16 pregnancies) were assigned to Subcutaneous Continuous Preprogrammed Insulin Infusion (SCII) because of high risk pregnancies (HRP) (at least one of the following former history of spontaneous abortions, stillbirths, premature deliveries and/or sterility). The remaining 12 PDPs (15 pregnancies with no past history of the above nature) were treated with Multiple Conventional Insulin Injections (MCII). Both groups were comparable regarding the following clinical parameters age, time of onset and class of diabetes. All patients were instructed in performing 3 to 7 daily Self Capillary Blood Glucose controls (SCBG). Mean follow-up observation period was (mean +/- SEM) 28.5 +/- 2.5 weeks for SCII and 3.2 MCII and 28.8 +/- 3.2 weeks for MCII. All the 3 PDP drop outs (4 pregnancies) belonged to the CMII group. No drop outs were recorded in the SCII group. Both insulin therapy approaches were similarly effective in improving metabolic control in that comparable levels of mean blood glucose (MBG) and HbA1 were attained by SCII and MCII (Fig. 1). Compliance, as evidenced by average of daily SCBG was also similar in both groups (Fig. 2). Such satisfactory metabolic control was achieved mostly because of an increase in the percentage (65
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Coleções: 06-national / AR Base de dados: BINACIS Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 1992 Tipo de documento: Article País de publicação: Argentina
Buscar no Google
Coleções: 06-national / AR Base de dados: BINACIS Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 1992 Tipo de documento: Article País de publicação: Argentina