Cuantificación de células productoras de gastrina (celulas G) en gastritis crónica. / [Quantification of gastrin-producing cells (G cells) in chronic gastritis]
Acta gastroenterol. latinoam
; Acta gastroenterol. latinoam;13(2): 141-4, 1983.
Article
em Es
| BINACIS
| ID: bin-49778
Biblioteca responsável:
AR40.1
ABSTRACT
The gastrin-producing G-cells of the antropyloric mucosa are affected by a variety of disorders. By immunoperoxidase methods, employing a specific anti-gastrin I and II antibody, we demonstrated G cells in antropyloric biopsies of 15 patients with chronic gastritis, 6 of them with gastric ulcer and 1 with duodenal ulcer disease. As controls we studied 5 biopsies of histologically normal antropyloric mucosa. We correlated the numbers of G cells per gland with the histological, clinical and endoscopic findings. Normal antropyloric mucosa contained a mean of 2.11 G cells per gland. Patients with chronic gastritis had decreased numbers of G cells (mean 0.75) The difference was statistically significant. The cases with chronic gastritis and intestinal metaplasia had lower numbers of G cells (mean 0.38). The case with duodenal ulcer had a number of G-cells similar of normal cases (1.57). This finding give a morphologic basis for the low gastrin serum levels usually present in these entities.
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Coleções:
06-national
/
AR
Base de dados:
BINACIS
Idioma:
Es
Revista:
Acta gastroenterol. latinoam
Ano de publicação:
1983
Tipo de documento:
Article
País de publicação:
Argentina