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Transplantation of islets of Langerhans in diabetic rats
Boschero, A C; Negreiros de Paiva, C E.
Afiliação
  • Boschero, A C; s.af
  • Negreiros de Paiva, C E; s.af
Acta physiol. latinoam ; 27(1): 1-6, 1977.
Article em Es | LILACS-Express | BINACIS | ID: biblio-1158522
Biblioteca responsável: AR1.1
Localização: [{"text": "AR1.1"}]
ABSTRACT
In the present work, homogeneous isolated pancreatic islet-cells were transplanted to diabetic rats with the aim of verifying if the transplanted tissue could survive and reduce the plasma glucose concentration on the alloxan-induced diabetic receptors. For the isolation of the pancreatic islets, pancreas was incubated in collagenase solution for about 13 +/- 3 minutes, followed by centrifugation in Ficoll gradients. The islets, 3 000 to 5 000, were transplanted to alloxan diabetic recipients, in a territory, preferentially with portal-hepatic drainage (mesentery and spleen). Sixty per cent of the recipients exhibited a fall of the plasma glucose concentration, up to 70
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Coleções: 06-national / AR Base de dados: BINACIS Idioma: En / Es Revista: Acta Physiol Lat Am / Acta physiol. latinoam Ano de publicação: 1977 Tipo de documento: Article País de publicação: Argentina
Buscar no Google
Coleções: 06-national / AR Base de dados: BINACIS Idioma: En / Es Revista: Acta Physiol Lat Am / Acta physiol. latinoam Ano de publicação: 1977 Tipo de documento: Article País de publicação: Argentina