Vasodilatadores en arterias radiales humanas aisladas.

Rinaldi, G; Navia, D; Vaccarino, G; Segura, E; Albertal, J

Vasodilatadores en arterias radiales humanas aisladas. / [Vasodilators in isolated human radial arteries]

Rinaldi, G; Navia, D; Vaccarino, G; Segura, E; Albertal, J.

Afiliação

Albertal, J; Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina. rinaldi@nahuel.biol.unlp.edu.ar.

Medicina (B.Aires) ; 60(4): 420-6, 2000.

Article em Es | BINACIS | ID: bin-39685

Biblioteca responsável: AR2.1

ABSTRACT

ABSTRACT

This paper was designed to evaluate the effectivity of several vasodilators, applied topically, to attenuate the hyperreactivity of radial arteries (RA) implanted as aorto-coronary bypass. Remnant segments of the RA were obtained from 20 operations, and each of the segments was divided into 4 rings. The rings were incubated for 30 minutes in control conditions (n = 20) or in presence of 30 microM of Diltiazem (DILT, n = 6), 30 microM of mibefradil (MIBE, n = 4) or a mixture of 30 microM of verapamil + 30 microM of nitroglycerin (VP-NTG, n = 6). A subsequent exposure to KCl 80 mM (in absence of vasodilators) evoked a sustained contraction in control rings, which was attenuated by 35 +/- 9

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Coleções: 06-national / AR Base de dados: BINACIS Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 2000 Tipo de documento: Article País de publicação: Argentina

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