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Acidos grasos de fosfolípidos en plasma y eritrocitos de lactantes desnutridos alimentados con leche materna o fórmulas. / [Fatty acids of plasma and erythrocyte phospholipids in malnourished infants well-fed by breast feeding or formula]
Marin, M C; Rey, G E; Rodrigo, M A; de Alaniz, M J.
Afiliação
  • de Alaniz, M J; Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Argentina. mmarin@atlas.med.unlp.edu.ar.
Medicina (B.Aires) ; 61(1): 41-8, 2001.
Article em Es | BINACIS | ID: bin-39578
Biblioteca responsável: AR2.1
ABSTRACT
Polyunsaturated fatty acids (PUFA) derived from essential fatty acids (EFA) play an important role in prenatal visual and neural development. Protein-energy malnutrition affects PUFA supply, and hence the synthesis of structural lipids during growth. Recently, some physiological studies reported abnormalities in the neurological functions of formula-fed infants relative to breast-fed. The purpose of our study was to assess whether fatty acid composition of the malnourished infant diet modifies plasma and erythrocyte phospholipid fatty acid composition. Three groups of full-term malnourished infants were selected according to their prior feeding. Two groups had received commercial formulas, one of them supplied with linoleic and alpha-linolenic acid, and the other supplied in addition with long chain PUFA from n-3 and n-6 series. The reference group of breast-fed infants was also enrolled. Plasma and erythrocyte phospholipid fatty acid composition was determined by gas-liquid chromatography. Those infants receiving formulas showed in plasma and erythrocyte phospholipids increased values in total saturated and monoethylenic fatty acids, and decreased values in polyunsaturated fatty acids from both n-6 and n-3 series, relative to that of breast-fed infants. These differences were more remarkable in the case of infants who received formula without PUFA. We conclude that in malnourished infants, a nutrient formula enriched with long chain fatty acids of n-6 and n-3 series could be helpful to achieve an erythrocyte and plasma fatty acid pattern similar to that obtained in breast-fed infants.
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Coleções: 06-national / AR Base de dados: BINACIS Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 2001 Tipo de documento: Article País de publicação: Argentina
Buscar no Google
Coleções: 06-national / AR Base de dados: BINACIS Idioma: Es Revista: Medicina (B.Aires) Ano de publicação: 2001 Tipo de documento: Article País de publicação: Argentina