Acidos grasos de fosfolípidos en plasma y eritrocitos de lactantes desnutridos alimentados con leche materna o fórmulas. / [Fatty acids of plasma and erythrocyte phospholipids in malnourished infants well-fed by breast feeding or formula]
Medicina (B.Aires)
; 61(1): 41-8, 2001.
Article
em Es
| BINACIS
| ID: bin-39578
Biblioteca responsável:
AR2.1
ABSTRACT
Polyunsaturated fatty acids (PUFA) derived from essential fatty acids (EFA) play an important role in prenatal visual and neural development. Protein-energy malnutrition affects PUFA supply, and hence the synthesis of structural lipids during growth. Recently, some physiological studies reported abnormalities in the neurological functions of formula-fed infants relative to breast-fed. The purpose of our study was to assess whether fatty acid composition of the malnourished infant diet modifies plasma and erythrocyte phospholipid fatty acid composition. Three groups of full-term malnourished infants were selected according to their prior feeding. Two groups had received commercial formulas, one of them supplied with linoleic and alpha-linolenic acid, and the other supplied in addition with long chain PUFA from n-3 and n-6 series. The reference group of breast-fed infants was also enrolled. Plasma and erythrocyte phospholipid fatty acid composition was determined by gas-liquid chromatography. Those infants receiving formulas showed in plasma and erythrocyte phospholipids increased values in total saturated and monoethylenic fatty acids, and decreased values in polyunsaturated fatty acids from both n-6 and n-3 series, relative to that of breast-fed infants. These differences were more remarkable in the case of infants who received formula without PUFA. We conclude that in malnourished infants, a nutrient formula enriched with long chain fatty acids of n-6 and n-3 series could be helpful to achieve an erythrocyte and plasma fatty acid pattern similar to that obtained in breast-fed infants.
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Coleções:
06-national
/
AR
Base de dados:
BINACIS
Idioma:
Es
Revista:
Medicina (B.Aires)
Ano de publicação:
2001
Tipo de documento:
Article
País de publicação:
Argentina