Inmunofenotipos aberrantes en leucemias agudas en una población hospitalaria de Buenos Aires. / [Aberrant immunophenotypes in acute leukemia in a Buenos Aires hospital population].
Medicina (B.Aires)
; Medicina (B.Aires);73(1): 9-16, 2013.
Article
em Es
| BINACIS
| ID: bin-133230
ABSTRACT
Multiparameter flow cytometry (MFC) has become the preferred method for the lineage assignment and maturational analysis of malignant cells in acute leukemias. Multiparametric immunophenotyping analysis allows the detection of aberrant antigen expression and the analysis of heterogeneity and clonality of malignant cells in leukemias. Our objectives were to analyze the membrane antigen expression and to evaluate if the aberrant phenotypes occurrence in blasts cells of patients with acute leukemia is useful in monitoring the response to the treatment. We have retrospectively analyzed the MFC data of 364 samples sent to our laboratory in a 7 years period. For this purpose we have used a large panel of monoclonal antibodies against lymphoid, myeloid and precursors antigens. From the 364 analyzed samples, 60.2
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Coleções:
06-national
/
AR
Base de dados:
BINACIS
Assunto principal:
Leucemia
/
Antígenos CD
/
Imunofenotipagem
Tipo de estudo:
Observational_studies
Limite:
Aged80
País/Região como assunto:
America do sul
/
Argentina
Idioma:
Es
Revista:
Medicina (B.Aires)
Ano de publicação:
2013
Tipo de documento:
Article
País de publicação:
Argentina