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Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
Ebrahimzadeh, Mohammad Ali; Khalili, Masoumeh; Jafari, Negar; Zareh, Giti; Farzin, Davood; Amin, Gholamreza.
Afiliação
  • Ebrahimzadeh, Mohammad Ali; Mazandaran University of Medical Sciences. School of Pharmacy. Pharmaceutical Sciences Research Center. Sari. IR
  • Khalili, Masoumeh; Golestan University of Medical Sciences. Neuroscience Research Center. Gorgan. IR
  • Jafari, Negar; Mazandaran University of Medical Sciences. School of Pharmacy. Pharmaceutical Sciences Research Center. Sari. IR
  • Zareh, Giti; Mazandaran University of Medical Sciences. School of Pharmacy. Pharmaceutical Sciences Research Center. Sari. IR
  • Farzin, Davood; Mazandaran University of Medical Sciences. School of Medicine. Department of Pharmacology. Sari. IR
  • Amin, Gholamreza; Tehran University of Medical Sciences. Faculty of Pharmacy. Department of Pharmacognosy. Tehran. IR
Braz. J. Pharm. Sci. (Online) ; 54(2): e17363, 2018. tab
Article em En | LILACS | ID: biblio-951923
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both plants exhibited significant anti-hypoxic activity and prolonged animal survival time. Anti-hypoia activity of C. pentaegyn was found to be superior to that of C. microphylla in circulatory and asphyctic hypoxia. Antihypoxic activity of these extracts may be attributed to their phenolic compounds.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Crataegus / Hipóxia Limite: Animals Idioma: En Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Crataegus / Hipóxia Limite: Animals Idioma: En Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil