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Solexa Profiling Identifies Differentially Expressed MiRNAs Between Sexually Immature and Mature Equine Testis
He, Liangjun; Wang, Shiwei; Deng, Haifeng; Dong, Hong; Chen, Jingbo.
Afiliação
  • He, Liangjun; Shihezi University. College of Animal Science. Shihezi. CN
  • Wang, Shiwei; Tarim University. College of Animal Science. Aral. CN
  • Deng, Haifeng; Zhaosu Horse Farm. Yili. CN
  • Dong, Hong; Shihezi University. College of Animal Science. Shihezi. CN
  • Chen, Jingbo; Xinjiang Academy of Animal Science. Institute of Animal Science. Urumqi. CN
Braz. arch. biol. technol ; Braz. arch. biol. technol;61: e18160122, 2018. tab, graf
Article em En | LILACS | ID: biblio-951498
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT MicroRNAs (miRNAs) are a class of short non-coding RNAs identified as potent regulators of gene expression. Previous studies have suggested that miRNAs are involved in mammalian spermatogenesis. Stallion fertility is an important trait for the horse breeding industry, but stallion fertility traits are largely ignored in the industry. In this study, we generated expression profiles of miRNAs in foal (immature) and stallion (mature) testes using Solexa sequencing. We identified 438 known and homologous equine miRNAs and 199 novel miRNAs which were distributed among all the chromosomes. The two developmental stages showed significant differences in miRNA expression patterns. Our result expands the horse miRNA database and provided additional information on the stallion fertility and possible spermatogenesis regulation through specific miRNAs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Braz. arch. biol. technol Assunto da revista: BIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Braz. arch. biol. technol Assunto da revista: BIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Brasil