Osteoradionecrosis of the jaws: case series treated with adjuvant low-level laser therapy and antimicrobial photodynamic therapy
J. appl. oral sci
; J. appl. oral sci;26: e20170172, 2018. tab, graf
Article
em En
| LILACS, BBO
| ID: biblio-893733
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Background:
Osteoradionecrosis of the jaw (ORNJ) is the most severe and complex sequel of head and neck radiotherapy (RT) because of the bone involved, it may cause pain, paresthesia, foul odor, fistulae with suppuration, need for extra oral communication and pathological fracture. We treated twenty lesions of ORNJ using low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT). The objective of this study was to stimulate the affected area to homeostasis and to promote the healing of the oral mucosa.Methods:
We performed aPDT on the exposed bone, while LLLT was performed around the bone exposure (red spectrum) and on the affected jaw (infrared spectrum). Monitoring and clinical intervention occurred weekly or biweekly for 2 years.Results:
100% of the sample presented clinical improvement, and 80% presented complete covering of the bone exposure by intact oral mucosa.Conclusion:
LLLT and aPDT showed positive results as an adjuvant therapy to treat ORNJ.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
BBO
/
LILACS
Assunto principal:
Osteorradionecrose
/
Fotoquimioterapia
/
Doenças Maxilomandibulares
/
Terapia com Luz de Baixa Intensidade
/
Quimiorradioterapia Adjuvante
/
Anti-Infecciosos
Tipo de estudo:
Evaluation_studies
/
Observational_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J. appl. oral sci
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil