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Physical properties and biological effects of mineral trioxide aggregate mixed with methylcellulose and calcium chloride
Lee, Bin-Na; Chun, Soo-Ji; Chang, Hoon-Sang; Hwang, Yun-Chan; Hwang, In-Nam; Oh, Won-Mann.
Afiliação
  • Lee, Bin-Na; Chonnam National University. School of Dentistry. Dental Science Research Institute, Department of Conservative Dentistry. Gwangju. KR
  • Chun, Soo-Ji; Chonnam National University. School of Dentistry. Dental Science Research Institute, Department of Conservative Dentistry. Gwangju. KR
  • Chang, Hoon-Sang; Chonnam National University. School of Dentistry. Dental Science Research Institute, Department of Conservative Dentistry. Gwangju. KR
  • Hwang, Yun-Chan; Chonnam National University. School of Dentistry. Dental Science Research Institute, Department of Conservative Dentistry. Gwangju. KR
  • Hwang, In-Nam; Chonnam National University. School of Dentistry. Dental Science Research Institute, Department of Conservative Dentistry. Gwangju. KR
  • Oh, Won-Mann; Chonnam National University. School of Dentistry. Dental Science Research Institute, Department of Conservative Dentistry. Gwangju. KR
J. appl. oral sci ; J. appl. oral sci;25(6): 680-688, Nov.-Dec. 2017. tab, graf
Article em En | LILACS, BBO | ID: biblio-893667
Biblioteca responsável: BR1.1
ABSTRACT
Abstract

Objectives:

Methylcellulose (MC) is a chemical compound derived from cellulose. MTA mixed with MC reduces setting time and increases plasticity. This study assessed the influence of MC as an anti-washout ingredient and CaCl2 as a setting time accelerator on the physical and biological properties of MTA. Material and

Methods:

Test materials were divided into 3 groups; Group 1(control) distilled water; Group 2 1% MC/CaCl2; Group 3 2% MC/CaCl2. Compressive strength, pH, flowability and cell viability were tested. The gene expression of bone sialoprotein (BSP) was detected by RT-PCR and real­ time PCR. The expression of alkaline phosphatase (ALP) and mineralization behavior were evaluated using an ALP staining and an alizarin red staining.

Results:

Compressive strength, pH, and cell viability of MTA mixed with MC/CaCl2 were not significantly different compared to the control group. The flowability of MTA with MC/CaCI2 has decreased significantly when compared to the control (p<.05). The mRNA level of BSP has increased significantly in MTA with MC/CaCl2 compared to the control (p<.05). This study revealed higher expression of ALP and mineralization in cells exposed to MTA mixed with water and MTA mixed with MC/CaCl2 compared to the control (p<.05).

Conclusions:

MC decreased the flowability of MTA and did not interrupt the physical and biological effect of MTA. It suggests that these cements may be useful as a root-end filling material.
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Texto completo: 1 Coleções: 01-internacional Base de dados: BBO / LILACS Assunto principal: Óxidos / Materiais Restauradores do Canal Radicular / Cloreto de Cálcio / Silicatos / Compostos de Cálcio / Compostos de Alumínio / Metilcelulose Limite: Animals Idioma: En Revista: J. appl. oral sci Assunto da revista: ODONTOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Coréia do Sul País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: BBO / LILACS Assunto principal: Óxidos / Materiais Restauradores do Canal Radicular / Cloreto de Cálcio / Silicatos / Compostos de Cálcio / Compostos de Alumínio / Metilcelulose Limite: Animals Idioma: En Revista: J. appl. oral sci Assunto da revista: ODONTOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Coréia do Sul País de publicação: Brasil