In Vitro Assessment of Antileishmanial Activity of Natamycin and Nystatin

Sidana, Arushdeep; Negi, Ajeet Kumar; Farooq, Umar

Sidana, Arushdeep; Negi, Ajeet Kumar; Farooq, Umar.

Afiliação

Sidana, Arushdeep; Shoolini University. Faculty of Applied Sciences and Biotechnology. Molecular and Immuno-parasitology Laboratory. Himachal Pradesh. IN
Negi, Ajeet Kumar; Shoolini University. Faculty of Applied Sciences and Biotechnology. Molecular and Immuno-parasitology Laboratory. Himachal Pradesh. IN
Farooq, Umar; Shoolini University. Faculty of Applied Sciences and Biotechnology. Molecular and Immuno-parasitology Laboratory. Himachal Pradesh. IN

Braz. arch. biol. technol ; Braz. arch. biol. technol;60: e17160368, 2017. tab, graf

Article em En | LILACS | ID: biblio-839083

Biblioteca responsável: BR1.1

ABSTRACT

ABSTRACT

ABSTRACT The present study was aimed to evaluate the in vitro antileishmanial activity of four different concentrations of natamycin and nystatin by using MTT 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyl tetrazolium bromide reduction assay. In vitro antileishmanial activity revealed that the IC50 of natamycin (80.49 μg/ml) and nystatin (105.7 μg/ml) was less than that of sodium stibogluconate (127.9 μg/ml), and more than amphotericin B (18.91 μg/ml).

Palavras-chave

Antileishmanial; Leishmania donovani; Leishmaniasis; Natamycin; Nystatin

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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Braz. arch. biol. technol Assunto da revista: BIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia País de publicação: Brasil

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