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Endocan may predict the presence of coronary slow flow and coronary artery disease
Efe, Muhammet Mucip; Akyüz, Aydın; Aydın, Cihan; Demirkıran, Aykut; Alpsoy, Şeref.
Afiliação
  • Efe, Muhammet Mucip; Namık Kemal University. Faculty of Medicine. Department of Cardiology. Tekirdağ. TR
  • Akyüz, Aydın; Namık Kemal University. Faculty of Medicine. Department of Cardiology. Tekirdağ. TR
  • Aydın, Cihan; Namık Kemal University. Faculty of Medicine. Department of Cardiology. Tekirdağ. TR
  • Demirkıran, Aykut; Namık Kemal University. Faculty of Medicine. Department of Cardiology. Tekirdağ. TR
  • Alpsoy, Şeref; Namık Kemal University. Faculty of Medicine. Department of Cardiology. Tekirdağ. TR
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);70(8): e20240515, 2024. tab
Article em En | LILACS-Express | LILACS | ID: biblio-1575535
Biblioteca responsável: BR1.1
ABSTRACT
SUMMARY

OBJECTIVE:

Coronary artery disease (CAD) is frequent, but coronary slow flow (CSF) is a less common cardiovascular disease with a significant risk of mortality and morbidity. Endocan is a proinflammatory glycopeptide that has been investigated in cardiovascular diseases as well as some inflammatory diseases in recent years. We planned to compare the levels of endocan in both CAD and CSF in a similar population and examine the relationship of endocan with additional clinical variables. MATERIALS AND

METHODS:

In the trial, we included 169 consecutive subjects having a coronary angiography indication. According to the results of coronary angiography, 58 people were included in the CAD group, 52 were in the CSF group, and 59 people were in the control group. The control group includes those who did not have any lesions in their epicardial coronary arteries. Thrombolysis in myocardial infarction (TIMI)-frame counts (TFC) were calculated for all patients.

RESULTS:

Notably, 2.6% of the population in our study had CSF. Both the CAD (555±223 pg/mL) and CSF (559±234 pg/mL) groups had higher endocan levels than the control group (331±252 pg/mL) (p<0.001). There were similar endocan levels between the CAD and CSF groups. Endocan levels were shown to be favorably associated with mean TFC (r=0.267; p0.001). Serum endocan levels (particularly those above 450 pg/mL) and the presence of hyperlipidemia were the most important predictors of both CAD and CSF.

CONCLUSION:

Endocan levels are higher in CAD and CSF patients than in those with normal coronary arteries.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. Assoc. Med. Bras. (1992, Impr.) Assunto da revista: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. Assoc. Med. Bras. (1992, Impr.) Assunto da revista: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil