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Serum progesterone, glycosylated hemoglobin and insulin levels with the risk of premature rupture of membranes in gestational diabetes mellitus
Zhou, LiRong; Xiong, XueSong; Chen, LianHua.
Afiliação
  • Zhou, LiRong; Hubei University of Medicine. Affiliated Sinopharm Dongfeng General Hospital. Department of Endocrinology and Metabolism. Shiyan City. CN
  • Xiong, XueSong; Ezhou Central Hospital. Department of Endocrinology. Ezhou City. CN
  • Chen, LianHua; The Affiliated Peoples Hospital of Hubei University of Medicine. Shiyan Renmin Hospital. Department of Nursing. Shiyan City. CN
Clinics ; Clinics;79: 100461, 2024. tab, graf
Article em En | LILACS-Express | LILACS | ID: biblio-1574750
Biblioteca responsável: BR1.1
ABSTRACT
Abstract

Objective:

To discuss the correlation between serum progesterone, glycosylated Hemoglobin (HbA1c), and insulin levels in pregnant women with Gestational Diabetes Mellitus (GDM) and the risk of Premature Rupture of Membranes (PROM).

Methods:

A retrospective analysis was conducted on 52 patients diagnosed with GDM who also presented with PROM (Observation group) and compared with 89 patients diagnosed with GDM but not complicated with PROM (Control group). Progesterone, insulin, and HbA1c were detected. Risk factors for PROM in GDM patients were analyzed.

Results:

The observation group had higher HbA1c and fasting blood glucose levels. Poor blood glucose control and GWG are risk factors for PROM in GDM patients. PROM increases adverse pregnancy outcomes in GDM. HbA1c, insulin, and HOMA-IR can predict the risk of PROM in GDM.

Conclusions:

The effective prediction of preterm PROM can be achieved through the monitoring of serum HbA1c, insulin levels, and insulin resistance in patients with GDM.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Clinics Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Brasil