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Lymphocyte Levels and Morbidity and Mortality in Cardiovascular Surgery With Cardiopulmonary Bypass
Castro, Renata Costa Café de; Costa, Paula Natividade; Rocha, Eduardo Augusto Victor; Ribeiro, Isabella Victoria da Cunha Peixoto; Parreira, Maria Paula.
Afiliação
  • Castro, Renata Costa Café de; Faculdade Ciências Médicas de Minas Gerais. Belo Horizonte. BR
  • Costa, Paula Natividade; Faculdade Ciências Médicas de Minas Gerais. Belo Horizonte. BR
  • Rocha, Eduardo Augusto Victor; Hospital Universitário Ciências Médicas. Department of Cardiac Surgery. Belo Horizonte. BR
  • Ribeiro, Isabella Victoria da Cunha Peixoto; Faculdade Ciências Médicas de Minas Gerais. Belo Horizonte. BR
  • Parreira, Maria Paula; Faculdade Ciências Médicas de Minas Gerais. Belo Horizonte. BR
Rev. bras. cir. cardiovasc ; Rev. bras. cir. cardiovasc;39(4): e20230136, 2024. tab
Article em En | LILACS-Express | LILACS | ID: biblio-1569621
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT

Introduction:

A year ago, in a sample of 113 patients, our research group found that a high number of lymphocytes in the immediate postoperative period was correlated to a poor prognosis in cardiovascular surgeries. This study is an expansion of the initial study in order to confirm this finding.

Methods:

We analyzed the data of 338 consecutive patients submitted to cardiovascular surgeries with cardiopulmonary bypass performed at Hospital Universitário Ciências Médicas (Belo Horizonte/Brazil) from 2015 to 2017. We analyzed 39 variables with the outcomes death, hospital stay, and intensive care unit stay.

Results:

The value of lymphocytes in the immediate postoperative period > 2175.0/mm³ was an indicator of poor prognosis in this sample (P<0.001). The variables female sex, age, high level of European System for Cardiac Operative Risk Evaluation II, increased stay in the intensive care unit and in the ward, elevation of creatinine in the preoperative period and at intensive care unit discharge, elevation of the percentage of immediate postoperative period segmented neutrophils, high immediate postoperative period neutrophil/lymphocyte ratio, fasting hyperglycemia, preoperative critical condition, reintubation, mild or transient acute renal failure, surgical infection, cardiopulmonary bypass, and aortic cross-clamping and mechanical ventilation durations also had an impact on the mortality outcome.

Conclusion:

The value of lymphocytes in the immediate postoperative period > 2175.0/mm3 was an indicator of poor prognosis in cardiovascular surgery with cardiopulmonary bypass.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. bras. cir. cardiovasc Assunto da revista: CARDIOLOGIA / CIRURGIA GERAL Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. bras. cir. cardiovasc Assunto da revista: CARDIOLOGIA / CIRURGIA GERAL Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil