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An investigation of the umbilical artery N-terminal proBrain natriuretic peptide levels of fetuses due to fetal distress in term pregnancies
Erturk, Derya; Birsen, Meryem Busra; Onder, Durmus; Kaba, Metin; Ellidag, Hamit Yasar; Inal, Zeynep Ozturk.
Afiliação
  • Erturk, Derya; Antalya Training and Research Hospital. Department of Obstetrics and Gynecology. Antalya. TR
  • Birsen, Meryem Busra; Antalya Training and Research Hospital. Department of Obstetrics and Gynecology. Antalya. TR
  • Onder, Durmus; Antalya Training and Research Hospital. Department of Obstetrics and Gynecology. Antalya. TR
  • Kaba, Metin; Antalya Training and Research Hospital. Department of Obstetrics and Gynecology. Antalya. TR
  • Ellidag, Hamit Yasar; Antalya Training and Research Hospital. Department of Biochemistry. Antalya. TR
  • Inal, Zeynep Ozturk; Konya City Hospital. Department of Obstetrics and Gynecology. Konya. TR
Rev. Assoc. Med. Bras. (1992, Impr.) ; Rev. Assoc. Med. Bras. (1992, Impr.);70(8): e20240446, 2024. tab
Article em En | LILACS-Express | LILACS | ID: biblio-1569461
Biblioteca responsável: BR1.1
ABSTRACT
SUMMARY

OBJECTIVE:

This study aimed to investigate umbilical artery N-terminal proBrain natriuretic peptide (NT-proBNP) in fetuses delivered by cesarean section due to fetal distress in term pregnancies.

METHODS:

This prospective case-control study was conducted at the Antalya Training and Research Hospital Obstetric Department, Turkiye. A total of 140 pregnant women, 70 underwent elective cesarean sections between weeks 37 and 40 of gestation (Group 1, the control group) and 70 underwent cesarean sections due to fetal distress (Group 2, the study group), were included. The participants' sociodemographic and obstetric data and fetal umbilical blood NT-proBNP levels were recorded in a database.

RESULTS:

Age, body mass index, gestational age, prenatal diagnostic tests, fetal anatomical scanning, and baby gender ratios were comparable between the groups (p>0.05), while statistically significant differences were observed in terms of gravidity (3.0 vs. 1.0, p≤0.001) and parity numbers (2 vs. 0, p≤0.001), baby height (50.36±0.88 vs. 49.80±0.86, p≤0.001) and weight (3422.43±409.16 vs. 3239.86±293.74, p=0.003), 1-min Apgar (9.0±0.1 vs. 8.5±1.3, p≤0.001) and 5-min Apgar (10.0±0.1 vs. 9.8±0.4, p=0.026) scores, umbilical artery pH (7.32±0.05 vs. 7.25±0.07, p≤0.001), umbilical artery base deficit (-2.48±1.23 vs. −4.36±1.09. p≤0.001), and NT-proBNP levels [8.77 (7.72-9.39) vs. 12.35 (9.69-12.92), p<0.001].

CONCLUSION:

This study showed that NT-proBNP can be used as an important marker in the diagnosis of fetal distress. Prospective studies with more participants are now needed to confirm the accuracy of our results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. Assoc. Med. Bras. (1992, Impr.) Assunto da revista: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Rev. Assoc. Med. Bras. (1992, Impr.) Assunto da revista: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil