Respiratory syncytial virus infection in children during SARS-CoV-2 pandemic at a referral center in Rio de Janeiro, Brazil
J. bras. pneumol
; J. bras. pneumol;50(3): e20240072, 2024. tab
Article
em En
|
LILACS-Express
| LILACS
| ID: biblio-1569303
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Objective:
In order to study the scenario of respiratory infections in pediatrics after the emergence of SARS-CoV-2 in Brazil, this study aimed to compare characteristics of children admitted for SARS or upper airway infection caused by either RSV or SARS-CoV-2.Methods:
This was a cross-sectional study involving children up to 48 months of age admitted to a tertiary pediatric hospital with a diagnosis of SARS or upper airway infection between April of 2020 and April of 2021. Respiratory secretion samples were collected 2-5 days after hospitalization, and antigen/PCR tests for viral etiologies were performed. In this analysis, patients with laboratorial diagnosis of SARS-CoV-2 and/or RSV were selected, and their clinical and epidemiological characteristics were compared using logistic regression.Results:
Our sample initially comprised 369 participants. SARS-CoV-2 and RSV infections were confirmed in 55 (15%) and 59 children (16%), respectively. Mean age was 12 months (0-48 months), and 47 were female. The following characteristics were significantly more frequent in patients with RSV when compared with those with COVID-19 younger age (OR = 0.94; 95% CI 0.90-0.98); lower frequency of fever (OR = 0.18; 95% CI 0.05-0.66); and more frequent upper airway symptoms cough (OR = 7.36; 95% CI 1.04-52.25); and tachypnea (OR = 6.06; 95% CI 1.31-28.0).Conclusions:
Children with RSV-related SARS were younger, had lower frequency of fever at admission, but had a higher frequency of signs of upper airway infection and lower systemic inflammation when compared with children hospitalized for COVID-19 during the first year of the pandemic.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
J. bras. pneumol
Assunto da revista:
PNEUMOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
/
Project document
País de afiliação:
Brasil
País de publicação:
Brasil