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Chemical composition and antifungal activity of Morinda Citrifolia fruit extract
Susilawati, Susilawati; Anwar, Chairil; Saleh, Masagus Irsan; Salni, Salni; Hermansyah, Hermansyah; Oktiarni, Dwita.
Afiliação
  • Susilawati, Susilawati; Universitas Sriwijaya. South Sumatra. ID
  • Anwar, Chairil; Sriwijaya Univerity. South Sumatra. ID
  • Saleh, Masagus Irsan; Sriwijaya Univerity. South Sumatra. ID
  • Salni, Salni; Sriwijaya Univerity. South Sumatra. ID
  • Hermansyah, Hermansyah; Sriwijaya Univerity. South Sumatra. ID
  • Oktiarni, Dwita; Universitas Bengkulu. Bengkulu. ID
Biosci. j. (Online) ; 39: e39076, 2023.
Article em En | LILACS-Express | LILACS | ID: biblio-1566370
Biblioteca responsável: BR396.4
ABSTRACT
Noni (Morinda citrifolia) fruit is a well-known plant used as a traditional medicine for preventing some diseases because of its abundance in chemical compounds. This research aimed to determine the phytochemical concentration, chemical composition, and antifungal activity of M. citrifolia fruit extract. M. citrifolia fruit was extracted with methanol and then distilled water for the partition extract. Subsequently, the extract was fractionated using various nonpolar to polar solutions, such as; chloroform, ethyl acetate, water, 2-propanol, and methanol fractions. Each fraction was evaporated until the dry extract was released. Additionally, the photochemical concentration of the M. citrifolia fruit extract was quantitatively determined using a UV-visible spectrophotometer. The chemical composition of the M. citrifolia fruit extract of each fraction was identified using gas chromatography-mass spectrometry (GC-MS). Then, the antifungal activity of M.citrifolia fruit extract against C. albicans and C. krusei was determined using the disc diffusion method. The results showed that the phytochemical concentration of the M. citrifolia fruit extract was 1970.25 ppm flavonoids, 35.61 ppm tannins, and 148.62 ppm steroids. 2-Fluorobenzoic acid, eucalyptol, 2-chloroaniline-5-sulfonic acid, hexa-decamethyl octasiloxane, and tetra-propyl stannane were found to be the major components of M. citrifolia fruit extract. According to the research, M. citrifolia fruit extract showed antifungal activity against C. albicans and C. krusei in all tested fractions. The maximum inhibition zone of C. albicans was 14.0 ± 1.00 mm in the 2-propanol fraction, while that of C. krusei was 11.7 ± 0.58 mm in the methanol fraction.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Biosci. j. (Online) Assunto da revista: Agricultura / Disciplinas das Ciˆncias Biol¢gicas / Pesquisa Interdisciplinar Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Indonésia País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Biosci. j. (Online) Assunto da revista: Agricultura / Disciplinas das Ciˆncias Biol¢gicas / Pesquisa Interdisciplinar Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Indonésia País de publicação: Brasil