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Unmet need for and impact of adopting immunobiological drugs for moderate to severe plaque psoriasis in a pediatric population
Palhano, Ana Clara Maia; Gutierrez, Ninna Medeiros; Santos, Nicolas Sousa Vecchio dos; Narikawa, Rita; Ballalai, André; Silva, Dimitri Luz Felipe da.
Afiliação
  • Palhano, Ana Clara Maia; Universidade de Santo Amaro. Dermatology Department. São Paulo. BR
  • Gutierrez, Ninna Medeiros; Hospital Israelita Albert Einstein. Faculdade Israelita de Ciências da Saúde Albert Einstein. São Paulo. BR
  • Santos, Nicolas Sousa Vecchio dos; Hospital Israelita Albert Einstein. Faculdade Israelita de Ciências da Saúde Albert Einstein. São Paulo. BR
  • Narikawa, Rita; Hospital Israelita Albert Einstein. Faculdade Israelita de Ciências da Saúde Albert Einstein. São Paulo. BR
  • Ballalai, André; Hospital Israelita Albert Einstein. Faculdade Israelita de Ciências da Saúde Albert Einstein. São Paulo. BR
  • Silva, Dimitri Luz Felipe da; Hospital Israelita Albert Einstein. Faculdade Israelita de Ciências da Saúde Albert Einstein. São Paulo. BR
Einstein (São Paulo, Online) ; 22: eGS0413, 2024. tab, graf
Article em En | LILACS-Express | LILACS | ID: biblio-1557719
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT Objective Therefore, this study aimed to evaluate the impact of secukinumab and ustekinumab against moderate-to-severe plaque psoriasis in a Brazilian pediatric population with access to public healthcare. Methods A survey of immunobiological treatments registered for use against pediatric psoriasis at the National Health Surveillance Agency was conducted. These treatments were compared to the list available in the same treatment category in the public health system through the Clinical Protocol and Therapeutic Guidelines for psoriasis. A quantitative analysis of the data of patients treated with immunobiological drugs the previous year in accordance with the Clinical Protocol and Therapeutic Guidelines was performed using data available in the DATASUS portal. Results The public budget impact scenarios analyzed were comparable to the investment already planned for acquiring the only available drug option. Conclusion The incorporation of two therapeutic options in the Clinical Protocol and Therapeutic Guidelines list for moderate-to-severe pediatric psoriasis was feasible in a horizon of 5 years compared to the investment into the single option available to pediatric patients. These findings can facilitate the local analysis of budgetary impact and discussions on the feasibility of this therapeutic incorporation at the state level.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Einstein (São Paulo, Online) Assunto da revista: Medicina Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Einstein (São Paulo, Online) Assunto da revista: Medicina Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil