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Transcriptome Analysis of Chicken Embryo Fibroblast Cell Infected with Mareks Disease Virus of GX0101 LTR
Li, X; Su, S; Cui, N; Zhou, H; Liu, X; Cui, Z.
Afiliação
  • Li, X; Shandong Agricultural University. College of Animal Science and Veterinary Medicine. Taian. CN
  • Su, S; Shandong Agricultural University. College of Animal Science and Veterinary Medicine. Taian. CN
  • Cui, N; Shandong Agricultural University. College of Animal Science and Veterinary Medicine. Taian. CN
  • Zhou, H; University of California. Department of Animal Science. Davis. US
  • Liu, X; Shandong Agricultural University. College of Animal Science and Veterinary Medicine. Taian. CN
  • Cui, Z; Shandong Agricultural University. College of Animal Science and Veterinary Medicine. Taian. CN
Rev. bras. ciênc. avic ; 19(2): 179-184, abr.-jun. 2017. tab, graf
Article em En | VETINDEX | ID: biblio-1490416
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT
Mareks disease (MD), a lymphoproliferative disorder of chickens caused by the MD virus (MDV), is economically significant. The resistance/susceptibility to MD is controlled by host genetics. The host response to different virus strains varies. The pathogenicity of REV-LTR deleted GX0101LTR MDV has been previously reported. However, the precise molecular mechanism of the response of chickens to GX0101LTR remains unclear. The current study aimed at identifying the genes and pathways involved in the response to GX0101LTR virus infection in specific pathogen-free chicken embryo fibroblast cells using global transcriptome analysis. A total of 1,633 genes associated with GX0101LTR infection were identified. Functional analysis showed that the cytokine-cytokine receptor interaction plays an important role in the response to GX0101LTR infection.
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Texto completo: 1 Base de dados: VETINDEX Assunto principal: Doença de Marek / Transcriptoma Limite: Animals Idioma: En Revista: Rev. bras. ciênc. avic Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Base de dados: VETINDEX Assunto principal: Doença de Marek / Transcriptoma Limite: Animals Idioma: En Revista: Rev. bras. ciênc. avic Ano de publicação: 2017 Tipo de documento: Article