Anti-SARS-CoV-2 antibody immunoreactivity profiles during COVID-19 recurrence
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;55: e0106, 2022. tab, graf
Article
em En
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LILACS-Express
| LILACS
| ID: biblio-1406963
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT Background:
This study aimed to evaluate IgG and IgM levels in COVID-19 recurrence.Methods:
The serum antibody levels and clinical data from 73 healthcare workers with SARS-CoV-2 divided into seroconverted (n=51) and non-seroconverted (n=22) groups were assessed. The presence of specific anti-nucleocapsid (anti-N) IgM and IgG for SARS-CoV-2 was evaluated. IgG antibodies to the SARS-CoV-2 spike receptor-binding domain were used to confirm non-seroconversion in all negative anti-N.Results:
Four recurrent cases displayed mild symptoms and were non-seroconverted until the recurrence of symptoms.Conclusions:
Undetectable anti-nucleocapsid IgM and IgG levels may be correlated with symptomatic COVID-19 recurrence.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil