Assessing ultrasonographic optic nerve sheath diameter in animal model with anesthesia regimens
Acta cir. bras
; 37(3): e370308, 2022. tab, graf, ilus
Article
em En
| VETINDEX
| ID: biblio-1383295
Biblioteca responsável:
BR68.1
Localização: BR68.1
ABSTRACT
Purpose:
To determine the normal optical nerve sheath (ONS) diameter ultrasonography (ONSUS) and evaluate the possible effects of drugs on ONS diameter during anesthetic induction in healthy pigs.Methods:
Healthy piglets were divided into three groups a control group, that received xylazine and ketamine (X/K); other that received xylazine, ketamine and propofol (X/K/P); and a third group that received xylazine, ketamine, and thiopental (X/K/T). The sheath diameter was assessed by ultrasonography calculating the average of three measurements of each eye from the left and right sides.Results:
118 animals were anesthetized (49 X/K 33 X/K/P and 39 X/K/T). Mean ONS sizes on both sides in each group were 0.394 ± 0.048 (X/K), 0.407 ± 0.029 (X/K/P) and 0.378 ± 0.042 cm (X/K/T) (medians of 0.400, 0.405 and 0.389, respectively). The ONS diameter varied from 0.287-0.512 cm (mean of 0.302 ± 0.039 cm). For group X/K, the mean diameter was 0.394 ± 0.048 cm. Significant differences in ONS sizes between the groups P and T (X/K/P > X/K/T, p = 0.003) were found. No statistically significant differences were detected when other groups were compared (X/K = X/K/P, p = 0.302; X/K = X/K/T, p = 0.294).Conclusions:
Sedation with thiopental lead to significative ONS diameter reduction in comparison with propofol. ONSUS may be useful to evaluate responses to thiopental administration.Palavras-chave
Texto completo:
1
Base de dados:
VETINDEX
Assunto principal:
Nervo Óptico
/
Suínos
/
Pressão Intracraniana
/
Ultrassonografia
/
Hipertensão Intracraniana
/
Anestesia
Limite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Ano de publicação:
2022
Tipo de documento:
Article