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A novel upper tract ureteroscopic biopsy technique: the "form tackle"
Klett, Dane E; Alom, Manaf; Wymer, Kevin; Potretzke, Aaron.
Afiliação
  • Klett, Dane E; Mayo Clinic. Department of Urology. Rochester. US
  • Alom, Manaf; Mayo Clinic. Department of Urology. Rochester. US
  • Wymer, Kevin; Mayo Clinic. Department of Urology. Rochester. US
  • Potretzke, Aaron; Mayo Clinic. Department of Urology. Rochester. US
Int. braz. j. urol ; 48(2): 367-368, March-Apr. 2022.
Article em En | LILACS | ID: biblio-1364961
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT Introduction and

Objective:

Upper tract urothelial carcinoma (UTUC) represents 5% of all urothelial malignancies (1-3). Accurate pathologic diagnosis is key and may direct treatment decisions. Current ureteroscopic biopsy techniques include cold-cup, backloaded cold-cup and stone basket (4-6). The study objective was to compare a standard cold-cup biopsy technique to a novel cold-cup biopsy technique and evaluate histopathologic results. Materials and

Methods:

We developed a novel UTUC biopsy technique termed the "form tackle" biopsy. Ureteroscope is passed into ureter/renal collecting system. Cold-cup forceps are opened and pressed into the lesion base (to engage the urothelial wall/submucosal tissue) then closed. Ureteroscope/forceps are advanced forward 3-10mm and then extracted from the patient. We compared standard versus novel upper tract biopsy techniques in a series of patients with lesions ≥1cm. In each procedure, two standard and two novel biopsies were obtained from the same lesion. The primary study aim was diagnosis of malignancy. IRB approved 21-006907.

Results:

Fourteen procedures performed on 12 patients between June 2020 and March 2021. Twenty-eight specimens sent (14 standard, 14 novel) (Two biopsies per specimen). Ten procedures with concordant pathology. In 4 procedures the novel biopsy technique resulted in a diagnosis of UTUC (2 high-grade, 2 low-grade) in the setting of a benign standard biopsy. Significant difference in pathologic diagnoses was detected between standard and novel upper tract biopsy techniques (p=0.008).

Conclusions:

The "form tackle" upper tract ureteroscopic biopsy technique provides higher tissue yield which may increase diagnostic accuracy. Further study on additional patients required. Early results are encouraging.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Neoplasias Ureterais / Biópsia / Carcinoma de Células de Transição Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Neoplasias Ureterais / Biópsia / Carcinoma de Células de Transição Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Brasil