Mantle cell lymphoma presenting with lethal atraumatic splenic rupture

Eyerer, Frederick; Gardner, Juli-Anne; Devitt, Katherine A

Eyerer, Frederick; Gardner, Juli-Anne; Devitt, Katherine A.

Afiliação

Eyerer, Frederick; University of Vermont Medical Center. Department of Pathology and Laboratory Medicine. Burlington. US
Gardner, Juli-Anne; University of Vermont Medical Center. Department of Pathology and Laboratory Medicine. Burlington. US
Devitt, Katherine A; University of Vermont Medical Center. Department of Pathology and Laboratory Medicine. Burlington. US

Autops. Case Rep ; 11: e2021340, 2021. graf

Article em En | LILACS | ID: biblio-1345359

Biblioteca responsável: BR26.7

ABSTRACT

ABSTRACT

Mantle cell lymphoma is characterized by t(11;14) with CCND1-IGH fusion and manifests with a spectrum of disease ranging from relatively indolent to aggressive. Here, we present a case of pleomorphic mantle cell lymphoma with three fusion signals that presented with lethal atraumatic splenic rupture. We discuss on the implications of variant CCND1 signal patterns as well as the epidemiology and pathophysiology of atraumatic splenic rupture.

Assuntos

Humanos; Masculino; Idoso; Ruptura Esplênica/patologia; Linfoma de Célula do Manto/epidemiologia; Esplenomegalia/complicações; Linfoma de Célula do Manto/fisiopatologia; Ciclina D

Palavras-chave

Cyclin D; Lymphoma, Malignant; Lymphoma, Mantle-Cell; Splenic Rupture

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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Ruptura Esplênica / Linfoma de Célula do Manto Limite: Aged / Humans / Male Idioma: En Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Brasil

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