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Antimicrobial Activity of Colloidal Selenium Nanoparticles in Chitosan Solution against Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans
Darroudi, Majid; Rangrazi, Abdolrasoul; Ghazvini, Kiarash; Bagheri, Hossein; Boruziniat, Alireza.
Afiliação
  • Darroudi, Majid; Mashhad University of Medical Sciences. Nuclear Medicine Research Center. Mashhad. IR
  • Rangrazi, Abdolrasoul; Mashhad University of Medical Sciences. Dental Research Center. Mashhad. IR
  • Ghazvini, Kiarash; Mashhad University of Medical Sciences. Antimicrobial Resistance Research Center. Mashhad. IR
  • Bagheri, Hossein; Mashhad University of Medical Sciences. Dental Materials Research Center. Mashhad. IR
  • Boruziniat, Alireza; Mashhad University of Medical Sciences. Dental Research Center. Mashhad. IR
Article em En | LILACS, BBO | ID: biblio-1250450
Biblioteca responsável: BR1264.1
ABSTRACT
ABSTRACT

Objective:

To investigate the antimicrobial activity of colloidal selenium nanoparticles in chitosan solution (Cts-Se-NPs) against Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans. Material and

Methods:

Cts-Se-NPs solution was prepared using a simple chemical reduction method. The MIC and MBC against S. mutans, L. acidophilus, and C. albicans were determined using the broth dilution assay.

Results:

The Cts-Se-NPs had remarkable antimicrobial activity against S. mutans, L. acidophilus, and C. albicans. The MIC values of the Cts-Se-NPs were lowest for S. mutans (0.068 mg/ml) compared to L. acidophilus (0.137 mg/ml), and C. albicans (0.274 mg/ml). The MBC values of the Cts-Se-NPs against the microorganisms after one, two, six, and 24 hours indicated that the concentration of 0.274 mg/ml of Cts-Se-NPs completely killed S. mutans, L. acidophilus, and C. albicans after one, two, and six hours, respectively. At the concentration of 0.137 mg/ml, S. mutans and L. acidophilus were killed after six and 24 hours, respectively.

Conclusion:

These findings encourage the potential use of Cts-Se-NPs in dentistry, while further clinical research is required in this area.
Assuntos
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Texto completo: 1 Coleções: 01-internacional Base de dados: BBO / LILACS Assunto principal: Selênio / Streptococcus mutans / Odontologia / Quitosana / Nanopartículas País/Região como assunto: Asia Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Assunto da revista: ODONTOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: BBO / LILACS Assunto principal: Selênio / Streptococcus mutans / Odontologia / Quitosana / Nanopartículas País/Região como assunto: Asia Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Assunto da revista: ODONTOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil