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Prevalence and risk factors for post-traumatic stress, anxiety, and depression in sepsis survivors after ICU discharge
Calsavara, Allan J.; Costa, Priscila A.; Nobre, Vandack; Teixeira, Antonio L..
Afiliação
  • Calsavara, Allan J.; Escola de Medicina, Universidade Federal de Ouro Preto (UFOP). Ouro Preto. BR
  • Costa, Priscila A.; Faculdade de Medicina, UFMG. Belo Horizonte. BR
  • Nobre, Vandack; Programa de Pós-Graduação em Ciências da Saúde, Infectologia e Medicina Tropical (PPG-IMT), Universidade Federal de Minas Gerais (UFMG). Belo Horizonte. BR
  • Teixeira, Antonio L.; Programa de Pós-Graduação em Ciências da Saúde, Infectologia e Medicina Tropical (PPG-IMT), Universidade Federal de Minas Gerais (UFMG). Belo Horizonte. BR
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; Braz. J. Psychiatry (São Paulo, 1999, Impr.);43(3): 269-276, May-June 2021. tab, graf
Article em En | LILACS | ID: biblio-1249196
Biblioteca responsável: BR1.1
ABSTRACT

Objective:

Sepsis survivors present a wide range of sequelae; few studies have evaluated psychiatric disorders after sepsis. The objective of this study was to define the prevalence of and risk factors for anxiety, depression and post-traumatic stress disorder (PTSD) symptoms in sepsis survivors.

Method:

Anxiety, depression and post-traumatic stress symptoms in severe sepsis and septic shock survivors 24 h and 1 year after intensive care unit (ICU) discharge were assessed using the Beck Anxiety/Depression Inventories and the PTSD Checklist-Civilian Version. Differences in psychiatric symptoms over time and the influence of variables on these symptoms were calculated with marginal models.

Results:

A total of 33 patients were enrolled in the study. The frequencies of anxiety, depression and PTSD 24 h after ICU discharge were 67%, 49%, and 46%, respectively and, among patients re-evaluated 1 year after ICU discharge, the frequencies were 38%, 50%, and 31%, respectively. Factors associated with PTSD included serum S100B level, age, and Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) score. Factors associated with depression included patient age and cumulative dose of dobutamine. IQCODE score and cumulative dose of haloperidol in the ICU were associated with anxiety after ICU discharge.

Conclusion:

Patients who survive sepsis have high levels of psychiatric symptoms. Sepsis and associated treatment-related exposures may have a role in increasing the risk of subsequent depression, anxiety, and PTSD.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Transtornos de Estresse Pós-Traumáticos / Sepse Tipo de estudo: Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Assunto da revista: PSIQUIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Transtornos de Estresse Pós-Traumáticos / Sepse Tipo de estudo: Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Assunto da revista: PSIQUIATRIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil