Bone lesions in leprosy
Int. j. lepr
; 30(2): 125-137, Apr.-Jun. 1962. ilus
Article
em En
| SES-SP, HANSEN, HANSENIASE, SESSP-ILSLACERVO, SES-SP
| ID: biblio-1228030
Biblioteca responsável:
BR191.1
Localização: [{"text": "BR191.1"}]
ABSTRACT
Enough is known of the occurrence of bone damage in leprosy to establish it as a serious and probably very frequent complication. For practical purposes although, other bones may be involved, the principal problem relates to the small bones of the hands and feet. Two general kinds of bone damage are recognized specific leprous osteitis, caused by invasion of the bone by M.leprae, and nonspecific leprous osteitis, in which the basic cause is damage or destruction due to invasion by M. leprae of the nerves supplying the extremities. The latter is nonspecific in the sense that the osteitis is not a direct result of invasion of the bone by the leprosy bacillus. From the mechanistic point of view, nonspecific osteitis may be tentatively classified as 1- Distal absorption, in which vascular disturbances and / or secondary infection in the anesthetic extremity play a role; 2- Metatarsophalangeal osteoarthritis, which is associated with repeated injury of an anesthetic site following displacement of the supporting structures of the plantar arch; 3- Osteitis, which is a sequel to ulceration and secondary infection; and 4- Osteoporosis, which follows disuse. There is a need for more extensive sequential studies, correlating clinical, x-ray and histopathologic data. It would be useful and enlightening to have such studies carried out in several widely separated parts of the world.
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Coleções:
06-national
/
BR
Base de dados:
HANSEN
/
HANSENIASE
/
SES-SP
/
SESSP-ILSLACERVO
Assunto principal:
Hanseníase
Idioma:
En
Revista:
Int. j. lepr
Ano de publicação:
1962
Tipo de documento:
Article