Your browser doesn't support javascript.
loading
Mycobacterium leprae typing by genomic diversity and global distribution of genotypes
Matsuoka, Masanori; Maeda, Shinji; Kai, Masanori; Nakata, Noboru; Chae, Gue-Tae; Gillis, Thomas P; Kobayashi, Kazuo; Izumi, Shinzo; Kashiwabara, Yoshiko.
Afiliação
  • Matsuoka, Masanori; National Institute of Infectious Disease. Leprosy Research Center. Tokyo. JP
  • Maeda, Shinji; National Institute of Infectious Disease. Leprosy Research Center. Tokyo. JP
  • Kai, Masanori; National Institute of Infectious Disease. Leprosy Research Center. Tokyo. JP
  • Nakata, Noboru; National Institute of Infectious Disease. Leprosy Research Center. Tokyo. JP
  • Chae, Gue-Tae; The Catholic University of Korea. College of Medicine. Institute of Hansen´s Disease. KR
  • Gillis, Thomas P; GWL Hanse´s Disease Center at Louisiana State University. Laboratory Research Branch. Molecular Biology Department. Baton Rouge. US
  • Kobayashi, Kazuo; National Institute of Infectious Disease. Leprosy Research Center. Tokyo. JP
  • Izumi, Shinzo; National Hospital Oshima Seishoem. Kagawa. JP
  • Kashiwabara, Yoshiko; National Institute of Infectious Disease. Leprosy Research Center. Tokyo. JP
Int. j. lepr. other mycobact. dis ; 68(2): 121-128, Jun., 2000. tab, graf, map
Article em En | SES-SP, HANSEN, HANSENIASE, SESSP-ILSLACERVO, SES-SP | ID: biblio-1226939
Biblioteca responsável: BR191.1
Localização: [{"text": "BR191.1"}]
ABSTRACT
The genetic diversity and related global distribution of 51 Mycobacterium leprae isolates were studied. Isolates were obtained from leprosy patients from 12 geographically distinct regions of the world and two were obtained from nonhuman sources. Polymerase chain reaction (PCR) followed by DNA sequencing was performed targeting the rpoT gene of M. leprae. Isolates were classified into two groups based on the number of tandem repeats composed of 6 base pairs in the rpoT gene. Isolates from Japan (except Okinawa) and Korea belonged to one group, while those from Southeast Asian countries, Brazil, Haiti and Okinawa in Japan belonged to a second genotype. M. leprae obtained from two nonhuman sources (an armadillo and a mangabey monkey) revealed the latter genotype. These results demonstrate the genetic diversity of M. leprae and the related genotype-specific distribution in the world.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google
Texto completo: 1 Coleções: 06-national / BR Base de dados: HANSEN / HANSENIASE / SES-SP / SESSP-ILSLACERVO Assunto principal: Genoma / Genótipo / Mycobacterium leprae Idioma: En Revista: Int. j. lepr. other mycobact. dis Ano de publicação: 2000 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google
Texto completo: 1 Coleções: 06-national / BR Base de dados: HANSEN / HANSENIASE / SES-SP / SESSP-ILSLACERVO Assunto principal: Genoma / Genótipo / Mycobacterium leprae Idioma: En Revista: Int. j. lepr. other mycobact. dis Ano de publicação: 2000 Tipo de documento: Article